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Natural and Synthetic Xanthonolignoids: Chemistry and Biological Activities

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Natural xanthonolignoids are formed by the coupling of cinnamyl alcohol with an appropriate ortho-dihydroxyxanthone. More than twenty xanthonolignoids have been isolated and synthesized and some interesting pharmacological activities of these compounds have been described.

The purpose of this review is to describe the natural occurrence, isolation, structure elucidation and synthesis - both biomimetic and classic -as well as biological activities of xanthonolignoids. Aspects related to biosynthesis will also be considered.

Keywords: Xanthonolignoids; cinnamyl alcohol; ortho-dihydroxyxanthone

Document Type: Review Article


Publication date: January 1, 2003

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  • Current Medicinal Chemistry covers all the latest and outstanding developments in medicinal chemistry and rational drug design. Each issue contains a series of timely in-depth reviews written by leaders in the field covering a range of the current topics in medicinal chemistry. Current Medicinal Chemistry is an essential journal for every medicinal chemist who wishes to be kept informed and up-to-date with the latest and most important developments.

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