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Polymer-Supported Metal-Phosphine Complexes for use as Catalysts or Linkers in Medicinally-Oriented Organic Synthesis

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Polymer-supported catalysts and reagents have found many uses in synthetic organic chemistry. This review discusses the preparation of polymer-supported phosphine ligands and organometallic complexes formed using these and highlights their use in reactions that are of particular interest to medicinal chemists. The scope of the review is limited to phosphine ligands and their metal complexes attached to derivitised polystyrene supports.

Keywords: combinatorial catalysis; metal-phosphine complexes; organometallic catalysis; polymer-supported catalysts; polystyrene; supported peptides

Document Type: Review Article


Publication date: December 1, 2002

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  • Current Medicinal Chemistry covers all the latest and outstanding developments in medicinal chemistry and rational drug design. Each issue contains a series of timely in-depth reviews written by leaders in the field covering a range of the current topics in medicinal chemistry. Current Medicinal Chemistry is an essential journal for every medicinal chemist who wishes to be kept informed and up-to-date with the latest and most important developments.

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