Applications of Peptide Mimetics in Cancer
Authors: Apostolopoulos, V.; Matsoukas, J.; Plebanski, M.; Mavromoustakos, T.
Source: Current Medicinal Chemistry, Volume 9, Number 4, February 2002 , pp. 411-420(10)
Publisher: Bentham Science Publishers
Abstract:The development of a vaccine for cancer has been difficult compared to the effective vaccines of infectious diseases. Most tumor antigens are not entirely foreign and are expressed on normal tissues, thus, making it difficult to induce strong immune responses against self antigens. A peptide mimic, however, may have the potential to generate greater immune responses than those induced to self peptides. In this review we discuss applications of peptide mimcs for cancer immunotherapy which may ultimately prove useful in humans.
Document Type: Review Article
Publication date: February 2002
- Current Medicinal Chemistry covers all the latest and outstanding developments in medicinal chemistry and rational drug design. Each issue contains a series of timely in-depth reviews written by leaders in the field covering a range of the current topics in medicinal chemistry. Current Medicinal Chemistry is an essential journal for every medicinal chemist who wishes to be kept informed and up-to-date with the latest and most important developments.