Skip to main content

New Trends in Extraction, Identification and Quantification of Artemisinin and its Derivatives

Buy Article:

$63.00 plus tax (Refund Policy)


Artemisinin, a sesquiterpene lactone endoperoxide, and a number of its precursors, metabolites and semisynthetic derivatives have shown to possess antimalarial properties. Several methods have been reported for the measurement of artemisinin and its main derivatives in plant material and biological fluids. However, most of them are either not sufficiently sensitive and do not offer reliable results, or are difficult to apply in routine analyses. Therefore, new m ethods for the determination of these compounds, such as supercritical fluid extraction and chromatography, pressurized solvent extraction, microwave-assisted extraction, high-performance liquid chromatography coupled to mass spectrometry or evaporative light scattering detection, will be presented. Applications to plant material, pharmaceutical formulations and biological fluids will also be reviewed.

Keywords: A. annua; Artemisia annua; Artemisinin; CAPILLARY ELECTROPHORESIS; ENZYME-LINKED IMMUNOSORBENT ASSAY; EVAPORATIVE LIGHT SCATTERING DETECTOR; HPLC-MS; HPLC-UV; Microwave-assisted Extraction; Pressurized solvent extraction (PSE); TANDEM MASS SPECTROMETRY; Thermolysis; arteannuin B; artemisinic acid; artemisitene; dihydroartemisinin

Document Type: Review Article


Publication date: 2001-12-01

More about this publication?
  • Current Medicinal Chemistry covers all the latest and outstanding developments in medicinal chemistry and rational drug design. Each issue contains a series of timely in-depth reviews written by leaders in the field covering a range of the current topics in medicinal chemistry. Current Medicinal Chemistry is an essential journal for every medicinal chemist who wishes to be kept informed and up-to-date with the latest and most important developments.
  • Access Key
  • Free ContentFree content
  • Partial Free ContentPartial Free content
  • New ContentNew content
  • Open Access ContentOpen access content
  • Partial Open Access ContentPartial Open access content
  • Subscribed ContentSubscribed content
  • Partial Subscribed ContentPartial Subscribed content
  • Free Trial ContentFree trial content
Cookie Policy
Cookie Policy
Ingenta Connect website makes use of cookies so as to keep track of data that you have filled in. I am Happy with this Find out more