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Biological Applications of Hammerhead Ribozymes as Anti-viral Molecules

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Abstract:

Ribozymes are catalytic RNAs that can cleave substrate RNAs in a sequence specific manner. Here we survey, in brief, the structure of hammerhead and hairpin ribozymes and discuss their applications as molecular antiviral molecules for HIV-1.

Keywords: Anti-viral Molecules; HAMMERHEAD RIBOZYME; Hammerhead Ribozymes; RIBOZYMES

Document Type: Review Article

DOI: http://dx.doi.org/10.2174/0929867013372373

Publication date: August 1, 2001

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  • Current Medicinal Chemistry covers all the latest and outstanding developments in medicinal chemistry and rational drug design. Each issue contains a series of timely in-depth reviews written by leaders in the field covering a range of the current topics in medicinal chemistry. Current Medicinal Chemistry is an essential journal for every medicinal chemist who wishes to be kept informed and up-to-date with the latest and most important developments.
ben/cmc/2001/00000008/00000010/art00004
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