Apoptosis at the Interface of Immunosuppressive and Anticancer Activities The Examples of Two Classes of Chemical Inducers, Oxysterols and Alkylating Agents
Keywords: DNA dependent protein kinase; Fas; NH2 methyl bis chloroethyl methylamine mustine; PARP inhibition; alkylatin agents; anticancer activities; antioxideants; antitumor effects; apoptotic death; cancer chemotherapy; caryolysine; chemical inducers; chlorambucil; chlormethine; cyclophosphamide; glutathione S transferase GST; ifosfamide; immunosuppressive; inhibition of cholesterol biosynthesis; mechlorethamine; melphalan; mustine; necrosis; nitrogen mustard; oxysterols; programmed cell death PCD; toxicity; tumor necrosis factor TNF receptor TNF R
Document Type: Review Article
Publication date: 01 July 2000
- Current Medicinal Chemistry covers all the latest and outstanding developments in medicinal chemistry and rational drug design. Each issue contains a series of timely in-depth reviews written by leaders in the field covering a range of the current topics in medicinal chemistry. Current Medicinal Chemistry is an essential journal for every medicinal chemist who wishes to be kept informed and up-to-date with the latest and most important developments.