Gossypol Prototype of Inhibitors Targeted to Dinucleotide Folds
Keywords: De Novo synthesis; IR Spectrum; NMR spectroscopy; acetic acid complex; american trypanosomiasis; antispernatigenic activity; cofactor binding; competive inhibitors of NAD H; crystalline hexaacetate; dihydroxynahthalenes; dinucleotide folds; gossylic iminolactone; gossylic lactone; gossypol; human immunodeficiency; hydrophobic residues; mammalian LDH; methlmagnesium bromide; multidrug resistant cells; oxazoline based chemistry; parasite lactate; perl acylated nitriles
Document Type: Review Article
Publication date: 01 April 2000
- Current Medicinal Chemistry covers all the latest and outstanding developments in medicinal chemistry and rational drug design. Each issue contains a series of timely in-depth reviews written by leaders in the field covering a range of the current topics in medicinal chemistry. Current Medicinal Chemistry is an essential journal for every medicinal chemist who wishes to be kept informed and up-to-date with the latest and most important developments.