Authors: Hilliard, Lucinda M.; Russo, Leileata M.; Comper, Wayne D.

Source: Current Hypertension Reviews, Volume 3, Number 1, February 2007 , pp. 29-37(9)

Publisher: Bentham Science Publishers

Abstract:

Albuminuria is the increased excretion of the serum protein albumin into the urine. Albuminuria is classically seen as an important diagnostic marker of declining kidney function, however, more recently albuminuria has also been implicated as a marker for cardiovascular and peripheral vascular disease indicating an important link between processes governing both cardiovascular and renal function. This review will discuss i) a common mechanism for albuminuria that accounts for albuminuria seen in hypertension and other albuminuric states and ii) possible linking factors between albuminuria, hypertension and cardiovascular disease.

Keywords: Albumin; albuminuria; angiotensin II; cardiovascular disease; degradation pathway; hypertension; microalbuminuria; renin-angiotensin system; transforming growth factor-β1

Document Type: Research article

DOI: http://dx.doi.org/10.2174/157340207779815563

Affiliations: 1: Department of Medicine, University of Melbourne, Austin Health, Heidelberg, Victoria, Australia 3084.

Publication date: 2007-02-01

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• Current Hypertension Reviews publishes frontier reviews on all the latest advances on hypertension and its related areas e.g. nephrology, clinical care, and therapy. The journal's aim is to publish the highest quality review articles dedicated to clinical research in the field. The journal is essential reading for all clinicians and researchers in the field of hypertension.