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Factors Affecting Sexual Transmission of HIV-1: Current Evidence and Implications for Prevention
Author: Chan, Derek J.
Source: Current HIV Research, Volume 3, Number 3, July 2005 , pp. 223-241(19)
Publisher: Bentham Science Publishers
Abstract:
The predominant mode of HIV-1 transmission globally is from sexual practices. The risk of HIV-1 transmission by sexual means is a function of infectivity, susceptibility and mode of transmission (type of sexual practice). In addition, transmission may be significantly increased or decreased by factors relating to the HIV-1 per se, sexual behaviour, other sexually transmissible infections (STIs), antiretroviral therapy (ART), spermicidal microbicides and HIV-1 vaccines, the host immune system, genital anatomy and nutritional deficiencies. Current research into the factors affecting sexual transmission of HIV-1 appears to benefit developed nations more than developing nations because of structured public health systems and the capacity to translate research findings into prevention strategies. A redistribution of global aid funding would do much to alleviate the pandemic in developed countries.Keywords: HIV-1 transmission; spermicidal microbicides; sexually transmissible infections (STIs)
Document Type: Review article
DOI: http://dx.doi.org/10.2174/1570162054368075
Affiliations: 1: lbion Street Centre, 150-154 Albion Street, Surry Hills, Sydney, New South Wales 2010, Australia.
Publication date: 2005-07-01
- Current HIV Research aims to cover all the latest and outstanding developments of HIV research. We invite comprehensive review articles and novel, pioneering work in the basic and clinical fields on all areas of HIV research, including virus replication and gene expression, HIV assembly, virus-cell interaction, viral pathogenesis, epidemiology and transmission, anti-retroviral therapy and adherence, drug discovery, the latest developments in HIV/AIDS vaccines and animal models, mechanisms and interactions with AIDS related diseases, social and public health issues related to HIV disease, and prevention of viral infection. Each issue of the journal contains a series of timely in-depth reviews and original research written by leaders in the field covering a range of current topics on HIV research. Periodically, the journal will invite guest editors to devote an issue on a particular area of HIV research of great interest that increases our understanding of the virus and its complex interaction with the host.
- In this: publication
- By this: publisher
- In this Subject: Medicine (General) , Public Health
- By this author: Chan, Derek J.
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