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Enzyme Inhibition Based Biosensors for Environmental Monitoring

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Abstract:

A review of methods based on enzyme inhibition in environmental monitoring is presented, which is mainly focussed on the detection of pollutants, such as pesticides, heavy metal ions and other toxic compounds. The sensing principles, design of the biosensor and an evaluation of biosensors structures (i.e. electrochemical, optical, piezoelectric and calorimetric) that have been developed for environmental monitoring are also emphasised. Finally, future prospects of the enzyme based biosensor are discussed, particularly in term of novel strategies required for application to the real samples.

Keywords: biosensors; environmental monitoring; enzyme inhibition based methods; toxic compounds

Document Type: Review Article

DOI: http://dx.doi.org/10.2174/157340805774580484

Affiliations: Department of Chemistry, and School of Pharmacy, University of Jember, Tegal Boto Campus, Jember 68121 Indonesia.

Publication date: November 1, 2005

More about this publication?
  • Current Enzyme Inhibition aims to publish all the latest and outstanding developments in enzyme inhibition studies with regards to the mechanisms of inhibitory processes of enzymes, recognition of active sites, and the discovery of agonists and antagonists, leading to the design and development of new drugs of significant therapeutic value. Each issue contains a series of timely, in-depth reviews written by leaders in the field, covering a range of enzymes that can be exploited for drug development. Current Enzyme Inhibition is an essential journal for every pharmaceutical and medicinal chemist who wishes to have up-to-date knowledge about each and every development in the study of enzyme inhibition.
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