Skip to main content

Therapeutic Approaches to Chronic Intestinal Inflammation by Specific Targeting of Mucosal IL-7 / IL-7R Signal Pathway

Buy Article:

$55.00 plus tax (Refund Policy)



Inflammatory bowel disease is thought to result from inappropriate activation of mucosal immune responses. Intestinal epithelial cells produce interleukin (IL)-7 that serves as a regulatory factor for IL-7 receptor (IL-7R)+ mucosal lymphocytes. The pivotal role of mucosal IL-7 / IL-7R dependent signals in the activation of mucosal immune responses that lead to the development of chronic intestinal inflammation are demonstrated. Therapeutic approaches targeting IL-7 / IL-7R signal pathway may be feasible in the treatment of inflammatory bowel disease.





No References
No Citations
No Supplementary Data
No Article Media
No Metrics

Keywords: ibd; il-7; il-7 receptor; mucosal immunity; t cells

Document Type: Review Article

Publication date: 2003-06-01

  • Access Key
  • Free content
  • Partial Free content
  • New content
  • Open access content
  • Partial Open access content
  • Subscribed content
  • Partial Subscribed content
  • Free trial content
Cookie Policy
X
Cookie Policy
Ingenta Connect website makes use of cookies so as to keep track of data that you have filled in. I am Happy with this Find out more