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CNS & Neurological Disorders - Drug Targets aims to cover all the latest and outstanding developments on the medicinal chemistry, pharmacology, molecular biology, genomics and biochemistry of contemporary molecular targets involved in neurological and central nervous system (CNS) disorders e.g. disease specific proteins, receptors, enzymes, genes. Each issue of the journal will contain a series of timely in-depth reviews written by leaders in the field covering a range of current topics on drug targets involved in neurological and CNS disorders. As the discovery, identification, characterization and validation of novel human drug targets for neurological and CNS drug discovery continues to grow; this journal will be essential reading for all pharmaceutical scientists involved in drug discovery and development.

Publisher: Bentham Science Publishers

Volume 4, Number 4, August 2005
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Book review

Editorial [Hot Topic: Neuron-Glia Interaction (Guest Editor: Joao O. Malva)]
pp. 317-317(1)
Author: Malva, Joao O.

Review article

Role of Nitric Oxide and Calpain Activation in Neuronal Death and Survival
pp. 319-324(6)
Authors: Araujo, I. M.; Carvalho, C. M.

What can Adenosine Neuromodulation do for Neuroprotection?
pp. 325-329(5)
Author: Ribeiro, J. A.

The Putative Neuroprotective Role of Neuropeptide Y in the Central Nervous System
pp. 331-347(17)
Authors: Silva, A. P.; Xapelli, S.; Grouzmann, E.; Cavadas, C.

Inflammation and Neurogenesis in Temporal Lobe Epilepsy
pp. 349-360(12)
Authors: Bernardino, L.; Ferreira, R.; Cristovao, A. J.; Sales, F.; Malva, J. O.

Molecular Targets and Therapeutic Strategies in Huntington's Disease
pp. 361-381(21)
Authors: Rego, A. C.; de Almeida, L. P.

Alzheimer's Disease-Associated Neurotoxic Mechanisms and Neuroprotective Strategies
pp. 383-403(21)
Authors: Pereira, C.; Agostinho, P.; Moreira, P. I.; Cardoso, S. M.; Oliveira, C. R.

Neurodegenerative Pathways in Parkinson's Disease: Therapeutic Strategies
pp. 405-419(15)
Authors: Cardoso, S. M.; Moreira, P. I.; Agostinho, P.; Pereira, C.; Oliveira, C. R.

Old and New Drug Targets in Diabetic Retinopathy: From Biochemical Changes to Inflammation and Neurodegeneration
pp. 421-434(14)
Authors: Leal, E. C.; Santiago, A. R.; Ambrosio, A. F.

Organotypic Hippocampal Slice Cultures for Studies of Brain Damage, Neuroprotection and Neurorepair
pp. 435-452(18)
Authors: Noraberg, J.; Poulsen, F. R.; Blaabjerg, M.; Kristensen, B. W.; Bonde, C.; Montero, M.; Meyer, M.; Gramsbergen, J. B.; Zimmer, J.

Liposomal and Viral Vectors for Gene Therapy of the Central Nervous System
pp. 453-465(13)
Authors: P. de Lima, M. C.; Girao da Cruz, M. T.; C. Cardoso, A. L.; Simoes, S.; de Almeida, L. P.

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Key:
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