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CNS & Neurological Disorders - Drug Targets aims to cover all the latest and outstanding developments on the medicinal chemistry, pharmacology, molecular biology, genomics and biochemistry of contemporary molecular targets involved in neurological and central nervous system (CNS) disorders e.g. disease specific proteins, receptors, enzymes, genes. Each issue of the journal will contain a series of timely in-depth reviews written by leaders in the field covering a range of current topics on drug targets involved in neurological and CNS disorders. As the discovery, identification, characterization and validation of novel human drug targets for neurological and CNS drug discovery continues to grow; this journal will be essential reading for all pharmaceutical scientists involved in drug discovery and development.

Publisher: Bentham Science Publishers

Volume 4, Number 1, February 2005
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Book review

Editorial [Hot Topic: Neurodegenerative Diseases (Guest Editor: Santosh R. D'Mello)]
pp. 1-1(1)
Authors: Santosh R. D'Mello

Review article

Treating Neurodegenerative Conditions Through the Understanding of Neuronal Apoptosis
pp. 3-23(21)
Authors: Santosh R. D'Mello; Paul C. Chin

Regulation of Neuronal Cell Death and Neurodegeneration by Members of the Bcl-2 Family: Therapeutic Implications
pp. 25-39(15)
Authors: John J. Shacka; Kevin A. Roth

Remodeling Chromatin and Stress Resistance in the Central Nervous System: Histone Deacetylase Inhibitors as Novel and Broadly Effective Neuroprotective Agents
pp. 41-50(10)
Authors: Brett Langley; JoAnn M. Gensert; M. F. Beal; Rajiv R. Ratan

Caspase Function in Neuronal Death: Delineation of the Role of Caspases in Ischemia
pp. 51-61(11)
Authors: Giselle F. Prunell; Valerie A. Arboleda; Carol M. Troy

Targeting the JNK Signaling Pathway for Stroke and Parkinson's Diseases Therapy
pp. 63-67(5)
Authors: Chia-Yi Kuan; Robert E. Burke

Mitochondria Play a Central Role in Estrogen-Induced Neuroprotection
pp. 69-83(15)
Authors: James W. Simpkins; Jian Wang; Xiaofei Wang; Evelyn Perez; Laszlo Prokai; James A. Dykens

Targeting Hypoxia-Inducible Factor (HIF) as a Therapeutic Strategy for CNS Disorders
pp. 85-92(8)
Authors: Robert S. Freeman; Maria C. Barone

Addendum

Author Index to Volume 3
pp. 93-94(2)
Author: Bentham Science Publishers

Subject Index to Volume 3
pp. 95-105(11)
Author: Bentham Science Publishers

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