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Current Drug Targets aims to cover the latest and most outstanding developments on the medicinal chemistry and pharmacology of molecular drug targets e.g. disease specific proteins, receptors, enzymes, genes. Each issue of the journal will be devoted to a single timely topic, with series of in-depth reviews, written by leaders in the field, covering a range of current topics on drug targets. These issues will be organized and led by a guest editor who is a recognized expert in the overall topic. As the discovery, identification, characterisation and validation of novel human drug targets for drug discovery continues to grow; this journal will be essential reading for all pharmaceutical scientists involved in drug discovery and development.

Publisher: Bentham Science Publishers

Volume 13, Number 14, December 2012

Articles

Editorial (Hot Topic: Translational Implications of Natural Agents)
pp. 1687-1688(2)
Author: Wahidur Rahman, KM

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Single Dose Oral Pharmacokinetic Profile of α-Mangostin in Mice
pp. 1698-1704(7)
Authors: Ramaiya, Atulkumar; Li, Gongbo; M. Petiwala, Sakina; J. Johnson, Jeremy

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Indole Compounds Against Breast Cancer: Recent Developments
pp. 1705-1719(15)
Authors: Biersack, Bernhard; Schobert, Rainer

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Anticarcinogenic Actions of Tributyrin, A Butyric Acid Prodrug
pp. 1720-1729(10)
Authors: Heidor, Renato; Festa Ortega, Juliana; de Conti, Aline; Prates Ong, Thomas; Salvador Moreno, Fernando

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Ent-11α-Hydroxy-15-Oxo-Kaur-16-en-19-Oic-Acid Induces Apoptosis of Human Malignant Cancer Cells
pp. 1730-1737(8)
Authors: Li, Ming-Yue; Ci Liang, Nian; G. Chen, George

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A Prooxidant Mechanism for the Anticancer and Chemopreventive Properties of Plant Polyphenols
pp. 1738-1749(12)
Authors: Yar Khan, Husain; Zubair, Haseeb; Fahad Ullah, Mohd; Ahmad, Aamir; Mumtaz Hadi, Sheikh

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Genistein Inhibits Cell Growth and Induces Apoptosis Through Up-regulation of miR-34a in Pancreatic Cancer Cells
pp. 1750-1756(7)
Authors: Xia, Jun; Duan, Qiaoling; Ahmad, Aamir; Bao, Bin; Banerjee, Sanjeev; Shi, Ying; Ma, Jia; Geng, Jian; Chen, Zhiwen; Wahidur Rahman, KM; Miele, Lucio; H Sarkar, Fazlul; Wang, Zhiwei

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Ascorbic Acid in Cancer Chemoprevention: Translational Perspectives and Efficacy
pp. 1757-1771(15)
Authors: F. Ullah, Mohammad; H. Bhat, Showket; Hussain, Eram; Abu-Duhier, Faisel; Ahmad, Aamir; M. Hadi, S.

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Baicalein - An Intriguing Therapeutic Phytochemical in Pancreatic Cancer
pp. 1772-1776(5)
Authors: Donald, Graham; Hertzer, Kathleen; Eibl, Guido

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From Body Art to Anticancer Activities: Perspectives on Medicinal Properties of Henna
pp. 1777-1798(22)
Authors: Pradhan, Rohan; Dandawate, Prasad; Vyas, Alok; Padhye, Subhash; Biersack, Bernhard; Schobert, Rainer; Ahmad, Aamir; H. Sarkar, Fazlul

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Chemopreventive and Chemotherapeutic Potential of Curcumin in Breast Cancer
pp. 1799-1819(21)
Authors: Sinha, Dona; Biswas, Jaydip; Sung, Bokyung; B. Aggarwal, Bharat; Bishayee, Anupam

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Mitosis-Targeting Natural Products for Cancer Prevention and Therapy
pp. 1820-1830(11)
Authors: V. Rao, Chinthalapally; D. Kurkjian, Carla; Y. Yamada, Hiroshi

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Apoptosis and Autophagy Induction As Mechanism of Cancer Prevention by Naturally Occurring Dietary Agents
pp. 1831-1841(11)
Authors: Mukhtar, Eiman; Mustafa Adhami, Vaqar; Khan, Naghma; Mukhtar, Hasan

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Cancer Chemoprevention with Green Tea Catechins: From Bench to Bed
pp. 1842-1857(16)
Authors: Shirakami, Yohei; Shimizu, Masahito; Moriwaki, Hisataka

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Targeting CSC-Related miRNAs for Cancer Therapy by Natural Agents
pp. 1858-1868(11)
Authors: Bao, Bin; Li, Yiwei; Ahmad, Aamir; S. Azmi, Asfar; Bao, Ginny; Ali, Shadan; Banerjee, Sanjeev; Kong, Dejuan; H. Sarkar, Fazlul

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DIMming Ovarian Cancer Growth
pp. 1869-1875(7)
Authors: K. Kandala, Prabodh; K. Srivastava, Sanjay

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Bioavailability Challenges Associated with Development of Saponins As Therapeutic and Chemopreventive Agents
pp. 1885-1899(15)
Authors: Gao, Song; Basu, Sumit; Yang, Zhen; Deb, Arijita; Hu, Ming

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Medicinal Properties of the Jamaican Pepper Plant Pimenta dioica and Allspice
pp. 1900-1906(7)
Authors: Zhang, Lei; L. Lokeshwar, Bal

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Androgen Receptor in Human Health: A Potential Therapeutic Target
pp. 1907-1916(10)
Authors: Rahman Siddique, Hifzur; Nanda, Sanjeev; Parray, Aijaz; Saleem, Mohammad

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