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Current Drug Targets aims to cover the latest and most outstanding developments on the medicinal chemistry and pharmacology of molecular drug targets e.g. disease specific proteins, receptors, enzymes, genes. Each issue of the journal will be devoted to a single timely topic, with series of in-depth reviews, written by leaders in the field, covering a range of current topics on drug targets. These issues will be organized and led by a guest editor who is a recognized expert in the overall topic. As the discovery, identification, characterisation and validation of novel human drug targets for drug discovery continues to grow; this journal will be essential reading for all pharmaceutical scientists involved in drug discovery and development.

Publisher: Bentham Science Publishers

Volume 13, Number 11, October 2012

Articles

Targeting Quorum Sensing and Competence Stimulation for Antimicrobial Chemotherapy
pp. 1348-1359(12)
Authors: E. Shepherd, Nicholas; S. Harrison, Rosemary; P. Fairlie, David

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Adaptors in Toll-Like Receptor Signaling and their Potential as Therapeutic Targets
pp. 1360-1374(15)
Authors: Ve, Thomas; J. Gay, Nicholas; Mansell, Ashley; Kobe, Bostjan; Kellie, Stuart

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Resolving Biofilm Infections: Current Therapy and Drug Discovery Strategies
pp. 1375-1385(11)
Authors: V. Ranall, Max; S. Butler, Mark; A. Blaskovich, Mark; A. Cooper, Matthew

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Uropathogenic Escherichia coli Mediated Urinary Tract Infection
pp. 1386-1399(14)
Authors: Totsika, Makrina; Gomes Moriel, Danilo; Idris, Adi; A. Rogers, Benjamin; J. Wurpel, Daniel; Phan, Minh-Duy; L. Paterson, David; A. Schembri, Mark

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Prokaryotic Substrate-Binding Proteins as Targets for Antimicrobial Therapies
pp. 1400-1410(11)
Authors: M. Counago, Rafael; A. McDevitt, Christopher; P. Ween, Miranda; Kobe, Bostjan

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RNA Interference for Viral Infections
pp. 1411-1420(10)
Authors: J. Blake, Stephen; F. Bokhari, Fawzi; A.J. McMillan, Nigel

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Wzy-Dependent Bacterial Capsules as Potential Drug Targets
pp. 1421-1431(11)
Authors: J. Ericsson, Daniel; Standish, Alistair; Kobe, Bostjan; Morona, Renato

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Recent Advances in the Development of Thioredoxin Reductase Inhibitors as Anticancer Agents
pp. 1432-1444(13)
Authors: Liu, Yang; Li, Yijing; Yu, Shenghui; Zhao, Guisen

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Co-Morbidity and Self Medication in Schizophrenia: Involvement of Endogenous Morphine Signaling Mechanisms
pp. 1454-1457(4)
Authors: M. Kream, Richard; Kuzelova, Hana; Kralickova, Milena; Ptacek, Radek; B. Stefano, George

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Recent Approaches to Novel Antibacterials Designed After LPS Structure and Biochemistry
pp. 1458-1471(14)
Authors: Gabrielli, Luca; Capitoli, Alice; Bini, Davide; Taraballi, Francesca; Lupo, Cristina; Russo, Laura; Cipolla, Laura

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