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Current Drug Targets aims to cover the latest and most outstanding developments on the medicinal chemistry and pharmacology of molecular drug targets e.g. disease specific proteins, receptors, enzymes, genes. Each issue of the journal will be devoted to a single timely topic, with series of in-depth reviews, written by leaders in the field, covering a range of current topics on drug targets. These issues will be organized and led by a guest editor who is a recognized expert in the overall topic. As the discovery, identification, characterisation and validation of novel human drug targets for drug discovery continues to grow; this journal will be essential reading for all pharmaceutical scientists involved in drug discovery and development.

Publisher: Bentham Science Publishers

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Volume 12, Number 14, December 2011

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Articles

Heat Shock Proteins: A Potential Anticancer Target
pp. 2001-2008(8)
Authors: K. Sankhala, Kamalesh; M. Mita, Monica; C. Mita, Alain; H. Takimoto, Chris

Vascular Disrupting Agents (VDA) in Oncology: Advancing Towards New Therapeutic Paradigms in the Clinic
pp. 2009-2015(7)
Authors: A. Spear, Matthew; LoRusso, Patricia; Mita, Alain; Mita, Monica

Blockade of Insulin-Like Growth Factor Type-1 Receptor with Cixutumumab (IMC-A12): A Novel Approach to Treatment for Multiple Cancers
pp. 2016-2033(18)
Authors: K. Rowinsky, Eric; D. Schwartz, Jonathan; Zojwalla, Naseem; Youssoufian, Hagop; Fox, Floyd; Pultar, Philippe; Novosyadlyy, Ruslan; Cosaert, Jan; L. Ludwig, Dale

The Emerging Role of Poly(ADP-Ribose) Polymerase Inhibitors in Cancer Treatment
pp. 2034-2044(11)
Authors: K. Sandhu, Shahneen; A. Yap, Timothy; S. de Bono, Johann

HGF/c-MET Targeted Therapeutics: Novel Strategies for Cancer Medicine
pp. 2045-2058(14)
Authors: A. Yap, Timothy; K. Sandhu, Shahneen; M. Alam, Salma; S. de Bono, Johann

The Pim Kinases: New Targets for Drug Development
pp. 2059-2066(8)
Authors: Swords, Ronan; Kelly, Kevin; Carew, Jennifer; Nawrocki, Stefan; Mahalingam, Devalingam; Sarantopoulos, John; Bearss, David; Giles, Francis

Targeting Aurora Kinases in Cancer Treatment
pp. 2067-2078(12)
Authors: R. Kelly, Kevin; Ecsedy, Jeffrey; Mahalingam, Devalingam; T. Nawrocki, Steffan; Padmanabhan, Swaminathan; J. Giles, Francis; S. Carew, Jennifer

Targeting Trail Towards the Clinic
pp. 2079-2090(12)
Authors: Mahalingam, Devalingam; N.A.M. Oldenhuis, Corina; Szegezdi, Eva; J. Giles, Francis; G.E. de Vries, Elisabeth; de Jong, Steven; T. Nawrocki, Steffan

The Hedgehog Knows Many Tricks
pp. 2091-2095(5)
Authors: J. Weiss, Glen; C. Mita, Alain; D. Von Hoff, Daniel

Molecular Players at the Intersection of Obesity and Osteoarthritis
pp. 2103-2128(26)
Authors: Luisa Bonet, M.; Granados, Nuria; Palou, Andreu

Novel Targets for Malaria Therapy
pp. 2129-2143(15)
Authors: Prabhu, Priyanka; Patravale, Vandana

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