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Current Drug Targets aims to cover the latest and most outstanding developments on the medicinal chemistry and pharmacology of molecular drug targets e.g. disease specific proteins, receptors, enzymes, genes. Each issue of the journal will be devoted to a single timely topic, with series of in-depth reviews, written by leaders in the field, covering a range of current topics on drug targets. These issues will be organized and led by a guest editor who is a recognized expert in the overall topic. As the discovery, identification, characterisation and validation of novel human drug targets for drug discovery continues to grow; this journal will be essential reading for all pharmaceutical scientists involved in drug discovery and development.

Publisher: Bentham Science Publishers

Volume 12, Number 14, December 2011

Articles

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Heat Shock Proteins: A Potential Anticancer Target
pp. 2001-2008(8)
Authors: K. Sankhala, Kamalesh; M. Mita, Monica; C. Mita, Alain; H. Takimoto, Chris

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Vascular Disrupting Agents (VDA) in Oncology: Advancing Towards New Therapeutic Paradigms in the Clinic
pp. 2009-2015(7)
Authors: A. Spear, Matthew; LoRusso, Patricia; Mita, Alain; Mita, Monica

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Blockade of Insulin-Like Growth Factor Type-1 Receptor with Cixutumumab (IMC-A12): A Novel Approach to Treatment for Multiple Cancers
pp. 2016-2033(18)
Authors: K. Rowinsky, Eric; D. Schwartz, Jonathan; Zojwalla, Naseem; Youssoufian, Hagop; Fox, Floyd; Pultar, Philippe; Novosyadlyy, Ruslan; Cosaert, Jan; L. Ludwig, Dale

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The Emerging Role of Poly(ADP-Ribose) Polymerase Inhibitors in Cancer Treatment
pp. 2034-2044(11)
Authors: K. Sandhu, Shahneen; A. Yap, Timothy; S. de Bono, Johann

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HGF/c-MET Targeted Therapeutics: Novel Strategies for Cancer Medicine
pp. 2045-2058(14)
Authors: A. Yap, Timothy; K. Sandhu, Shahneen; M. Alam, Salma; S. de Bono, Johann

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The Pim Kinases: New Targets for Drug Development
pp. 2059-2066(8)
Authors: Swords, Ronan; Kelly, Kevin; Carew, Jennifer; Nawrocki, Stefan; Mahalingam, Devalingam; Sarantopoulos, John; Bearss, David; Giles, Francis

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Targeting Aurora Kinases in Cancer Treatment
pp. 2067-2078(12)
Authors: R. Kelly, Kevin; Ecsedy, Jeffrey; Mahalingam, Devalingam; T. Nawrocki, Steffan; Padmanabhan, Swaminathan; J. Giles, Francis; S. Carew, Jennifer

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Targeting Trail Towards the Clinic
pp. 2079-2090(12)
Authors: Mahalingam, Devalingam; N.A.M. Oldenhuis, Corina; Szegezdi, Eva; J. Giles, Francis; G.E. de Vries, Elisabeth; de Jong, Steven; T. Nawrocki, Steffan

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The Hedgehog Knows Many Tricks
pp. 2091-2095(5)
Authors: J. Weiss, Glen; C. Mita, Alain; D. Von Hoff, Daniel

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Molecular Players at the Intersection of Obesity and Osteoarthritis
pp. 2103-2128(26)
Authors: Luisa Bonet, M.; Granados, Nuria; Palou, Andreu

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Novel Targets for Malaria Therapy
pp. 2129-2143(15)
Authors: Prabhu, Priyanka; Patravale, Vandana

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