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Current Drug Targets aims to cover the latest and most outstanding developments on the medicinal chemistry and pharmacology of molecular drug targets e.g. disease specific proteins, receptors, enzymes, genes. Each issue of the journal will be devoted to a single timely topic, with series of in-depth reviews, written by leaders in the field, covering a range of current topics on drug targets. These issues will be organized and led by a guest editor who is a recognized expert in the overall topic. As the discovery, identification, characterisation and validation of novel human drug targets for drug discovery continues to grow; this journal will be essential reading for all pharmaceutical scientists involved in drug discovery and development.

Publisher: Bentham Science Publishers

Volume 12, Number 6, June 2011

Articles

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Mild Mitochondrial Uncoupling as a Therapeutic Strategy
pp. 783-789(7)
Authors: M. Cunha, Fernanda; C. Caldeira da Silva, Camille; M. Cerqueira, Fernanda; J. Kowaltowski, Alicia

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Mitophagy in Neurodegeneration: An Opportunity for Therapy?
pp. 790-799(10)
Authors: X. Santos, R.; C. Correia, S.; Carvalho, C.; Cardoso, S.; S. Santos, M.; I. Moreira, P.

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Mitochondrial-Targeted Plastoquinone Derivatives. Effect on Senescence and Acute Age-Related Pathologies
pp. 800-826(27)
Authors: V. Skulachev, M.; N. Antonenko, Y.; N. Anisimov, V.; V. Chernyak, B.; A. Cherepanov, D.; A. Chistyakov, V.; V. Egorov, M.; G. Kolosova, N.; A. Korshunova, G.; G. Lyamzaev, K.; Y. Plotnikov, E.; A. Roginsky, V.; Y. Savchenko, A.; I. Severina, I.; F. Severin, F.; P. Shkurat, T.; N. Tashlitsky, V.; M. Shidlovsky, K.; Y. Vyssokikh, M.; A. Zamyatnin, A.; B. Zorov, D.; P. Skulachev, V.

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Mitochondrial Tolerance to Drugs and Toxic Agents in Ageing and Disease
pp. 827-849(23)
Authors: Suski, Jan; Lebiedzinska, Magdalena; G. Machado, Nuno; J. Oliveira, Paulo; Pinton, Paolo; Duszynski, Jerzy; R. Wieckowski, Mariusz

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Berberine as a Promising Safe Anti-Cancer Agent- Is there a Role for Mitochondria?
pp. 850-859(10)
Authors: V. Diogo, Catia; G. Machado, Nuno; A. Barbosa, Ines; L. Serafim, Teresa; Burgeiro, Ana; J. Oliveira, Paulo

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Mitochondria as a Target for Exercise-Induced Cardioprotection
pp. 860-871(12)
Authors: Ascensao, Antonio; Lumini-Oliveira, Jose; J. Oliveira, Paulo; Magalhaes, Jose

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Regulation of Mitochondrial Biogenesis in Metabolic Syndrome
pp. 872-878(7)
Authors: P. Rolo, Anabela; P. Gomes, Ana; M. Palmeira, Carlos

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Mitochondria in Chronic Liver Disease
pp. 879-893(15)
Authors: Grattagliano, Ignazio; Russmann, Stefan; Diogo, Catia; Bonfrate, Leonilde; J. Oliveira, Paulo; Q.-H. Wang, David; Portincasa, Piero

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The Adenine Nucleotide Translocase 2, a Mitochondrial Target for Anticancer Biotherapy
pp. 894-901(8)
Authors: Sharaf el dein, Ossama; Mayola, Eleonore; Chopineau, Joel; Brenner, Catherine

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The NK-1 Receptor: A New Target in Cancer Therapy
pp. 909-921(13)
Authors: Munoz, Miguel; Rosso, Marisa; Covenas, Rafael

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