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Current Drug Targets aims to cover the latest and most outstanding developments on the medicinal chemistry and pharmacology of molecular drug targets e.g. disease specific proteins, receptors, enzymes, genes. Each issue of the journal will be devoted to a single timely topic, with series of in-depth reviews, written by leaders in the field, covering a range of current topics on drug targets. These issues will be organized and led by a guest editor who is a recognized expert in the overall topic. As the discovery, identification, characterisation and validation of novel human drug targets for drug discovery continues to grow; this journal will be essential reading for all pharmaceutical scientists involved in drug discovery and development.

Publisher: Bentham Science Publishers

Volume 12, Number 5, May 2011

Articles

ABC Multidrug Transporters: Target for Modulation of Drug Pharmacokinetics and Drug-Drug Interactions
pp. 600-620(21)
Authors: Marquez, Beatrice; Van Bambeke, Francoise

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Improving Cancer Chemotherapy with Modulators of ABC Drug Transporters
pp. 621-630(10)
Authors: Shukla, S.; Ohnuma, S.; V. Ambudkar, S.

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ATP-Binding Cassette Transporters A1 and G1, HDL Metabolism, Cholesterol Efflux, and Inflammation: Important Targets for the Treatment of Atherosclerosis
pp. 647-660(14)
Authors: Ye, Dan; Lammers, Bart; Zhao, Ying; Meurs, Illiana; J.C. Van Berkel, Theo; Van Eck, Miranda

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The Canalicular Bile Salt Export Pump BSEP (ABCB11) as a Potential Therapeutic Target
pp. 661-670(10)
Authors: Stieger, Bruno; Beuers, Ulrich

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ABCC6 as a Target in Pseudoxanthoma Elasticum
pp. 671-682(12)
Authors: Varadi, Andras; Szabo, Zalan; Pomozi, Viola; de Boussac, Hugues; Fulop, Krisztina; Aranyi, Tamas

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ABC Subfamily D Proteins and Very Long Chain Fatty Acid Metabolism as Novel Targets in Adrenoleukodystrophy
pp. 694-706(13)
Authors: Morita, Masashi; Shimozawa, Nobuyuki; Kashiwayama, Yoshinori; Suzuki, Yasuyuki; Imanaka, Tsuneo

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The Ryanodine Receptor: A Pivotal Ca2+ Regulatory Protein and Potential Therapeutic Drug Target
pp. 709-723(15)
Authors: F. Dulhunty, Angela; G. Casarotto, Marco; A. Beard, Nicole

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Triple Threat: The Na+/Ca2+ Exchanger in the Pathophysiology of Cardiac Arrhythmia, Ischemia and Heart Failure
pp. 737-747(11)
Authors: Pott, Christian; Eckardt, Lars; I. Goldhaber, Joshua

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Targeting Calcium and the Mitochondria in Prevention of Pathology in the Heart
pp. 748-760(13)
Authors: M. Viola, Helena; C. Hool, Livia

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