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Current Drug Targets aims to cover the latest and most outstanding developments on the medicinal chemistry and pharmacology of molecular drug targets e.g. disease specific proteins, receptors, enzymes, genes. Each issue of the journal will be devoted to a single timely topic, with series of in-depth reviews, written by leaders in the field, covering a range of current topics on drug targets. These issues will be organized and led by a guest editor who is a recognized expert in the overall topic. As the discovery, identification, characterisation and validation of novel human drug targets for drug discovery continues to grow; this journal will be essential reading for all pharmaceutical scientists involved in drug discovery and development.

Publisher: Bentham Science Publishers

Volume 12, Number 4, April 2011

Articles

Mechanisms of Altered Cell Immunity and Cytotoxicity in COPD
pp. 450-459(10)
Authors: Tsoumakidou, M.; Tsiligianni, I.; Tzanakis, N.

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Airway Clearance of Apoptotic Cells in COPD
pp. 460-468(9)
Authors: R.S. Mukaro, Violet; Hodge, Sandra

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Oxidative Stress in Patients with COPD
pp. 469-477(9)
Authors: Loukides, Stelios; Bakakos, Petros; Kostikas, Konstantinos

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Respiratory Muscle Dysfunction in COPD: From Muscle to Cell
pp. 478-488(11)
Authors: Klimathianaki, M.; Vaporidi, K.; Georgopoulos, D.

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Immunologic Impact of Nutrient Depletion in Chronic Obstructive Pulmonary Disease
pp. 489-500(12)
Authors: Herzog, Ronit; Cunningham-Rundles, Susanna

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Pulmonary Hypertension in COPD: Pathophysiology and Therapeutic Targets
pp. 501-513(13)
Authors: Zakynthinos, E.; Daniil, Z.; Papanikolaou, J.; Makris, D.

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Pathophysiology of Airway Colonization in Critically ill COPD Patient
pp. 514-520(7)
Authors: Nseir, Saad; Ader, Florence; Lubret, Remy; Marquette, Charles-Hugo

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Mechanisms of Bacterial Resistance to Antibiotics in Infections of COPD Patients
pp. 521-530(10)
Authors: M. Kyd, Jennelle; McGrath, John; Krishnamurthy, Ajay

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Mechanism of Bioactive Transfer through Liposomal Bilayers
pp. 531-545(15)
Authors: Maherani, Behnoush; Arab-Tehrany, Elmira; Linder, Michel

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The Use of Structural Biology in Janus Kinase Targeted Drug Discovery
pp. 546-555(10)
Authors: L. Alicea-Velazquez, Nilda; J. Boggon, Titus

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Free Content The Molecular Mechanisms of Glucocorticoids-Mediated Neutrophil Survival
pp. 556-562(7)
Authors: S. Saffar, Arash; Ashdown, Heather; S. Gounni, Abdelilah

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Dasatinib: An Anti-Tumour Agent via Src Inhibition
pp. 563-578(16)
Authors: Gnoni, Antonio; Marech, Ilaria; Silvestris, Nicola; Vacca, Angelo; Lorusso, Vito

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Colloidal Carrier Systems for Transcutaneous Immunization
pp. 579-597(19)
Authors: N. Gupta, Prem; P. Vyas, Suresh

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