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Current Drug Targets aims to cover the latest and most outstanding developments on the medicinal chemistry and pharmacology of molecular drug targets e.g. disease specific proteins, receptors, enzymes, genes. Each issue of the journal will be devoted to a single timely topic, with series of in-depth reviews, written by leaders in the field, covering a range of current topics on drug targets. These issues will be organized and led by a guest editor who is a recognized expert in the overall topic. As the discovery, identification, characterisation and validation of novel human drug targets for drug discovery continues to grow; this journal will be essential reading for all pharmaceutical scientists involved in drug discovery and development.

Publisher: Bentham Science Publishers

Volume 11, Number 6, June 2010

Articles

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Anticancer Properties of Indole Compounds: Mechanism of Apoptosis Induction and Role in Chemotherapy
pp. 652-666(15)
Authors: Ahmad, Aamir; A Sakr, Wael; Wahidur Rahman, KM

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Targeting the p53-Family in Cancer and Chemosensitivity: Triple Threat
pp. 667-681(15)
Authors: Chung, J.; Irwin, M.S.

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EGFR(S) Inhibitors in the Treatment of Gastro-Intestinal Cancers: What's New?
pp. 682-698(17)
Authors: Singh Kanwar, Shailender; Nautiyal, Jyoti; P.N. Majumdar, Adhip

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Chemosensitization of Prostate Cancer by Modulating Bcl-2 Family Proteins
pp. 699-707(9)
Authors: Karnak, David; Xu, Liang

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Targeting Cellular Proapoptotic Molecules for Developing Anticancer Agents from Marine Sources
pp. 708-715(8)
Authors: Lin, Xiukun; Liu, Ming; Hu, Chaoxin; Joshua Liao, D.

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Carcinogenesis and Therapeutic Strategies in Thyroid Cancer
pp. 716-732(17)
Authors: Liu, Zhi-Min; Wu, Ting-Ting; Andrew van Hasselt, C.; G. Chen, George

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The Role of Notch Signaling Pathway in Epithelial-Mesenchymal Transition (EMT) During Development and Tumor Aggressiveness
pp. 745-751(7)
Authors: Wang, Zhiwei; Li, Yiwei; Kong, Dejuan; H. Sarkar, Fazlul

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The Use of Major Analgesics in Patients with Renal Dysfunction
pp. 752-758(7)
Authors: Niscola, Pasquale; Scaramucci, Laura; Vischini, Gisella; Giovannini, Marco; Ferrannini, Michele; Massa, Pasquale; Tatangelo, Paola; Galletti, Massimo; Palumbo, Roberto

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Human Arylamine N-Acetyltransferase 1: A Drug-Metabolizing Enzyme and a Drug Target?
pp. 759-766(8)
Authors: Rodrigues-Lima, Fernando; Dairou, Julien; Busi, Florent; Dupret, Jean-Marie

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