Current Drug Targets aims to cover the latest and most outstanding developments on the medicinal chemistry and pharmacology of molecular drug targets e.g. disease specific proteins, receptors, enzymes, genes. Each issue of the journal will be devoted to a single timely topic, with series of in-depth reviews, written by leaders in the field, covering a range of current topics on drug targets. These issues will be organized and led by a guest editor who is a recognized expert in the overall topic. As the discovery, identification, characterisation and validation of novel human drug targets for drug discovery continues to grow; this journal will be essential reading for all pharmaceutical scientists involved in drug discovery and development.

Publisher: Bentham Science Publishers

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Volume 11, Number 5, May 2010

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Articles

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Targets to Tackle - The Pathophysiology of the Disease
pp. 521-527(7)
Authors: Schmitz, N.; B. Kraus, V.; Aigner, T.

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Disease Modifying Osteoarthritis Drugs: Facing Development Challenges and Choosing Molecular Targets
pp. 528-535(8)
Author: Hellio Le Graverand-Gastineau, Marie-Pierre

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A Pathway and Approach to Biomarker Validation and Qualification for Osteoarthritis Clinical Trials
pp. 536-545(10)
Authors: J. Hunter, David; Losina, Elena; Guermazi, Ali; Burstein, Deb; N. Lassere, Marissa; Kraus, Virginia

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Intraarticular Treatments for Osteoarthritis: New Perspectives
pp. 546-560(15)
Author: Chevalier, Xavier

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Obesity and Inflammation - Targets for OA Therapy
pp. 586-598(13)
Authors: Iannone, F.; Lapadula, G.

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NF-κB Signaling: Multiple Angles to Target OA
pp. 599-613(15)
Authors: B. Marcu, Kenneth; Otero, Miguel; Olivotto, Eleonora; Maria Borzi, Rosa; B. Goldring, Mary

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Novel Therapies in OA
pp. 614-619(6)
Author: R. Flannery, Carl

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To Seek Shelter from the Wnt in Osteoarthritis? Wnt-Signaling as a Target for Osteoarthritis Therapy
pp. 620-629(10)
Authors: B. Blom, Arjen; L. van Lent, Peter; M. van der Kraan, Peter; B. van den Berg, Wim

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Treatment of Choroidal Neovascularization in High Myopia
pp. 630-644(15)
Authors: A. Montero, Javier; M. Ruiz-Moreno, Jose

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Targeting Interleukin-21 in Immune-Mediated Pathologies
pp. 645-649(5)
Authors: Sarra, Massimiliano; Pallone, Francesco; T. Macdonald, Thomas; Monteleone, Giovanni

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