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Current Drug Targets aims to cover the latest and most outstanding developments on the medicinal chemistry and pharmacology of molecular drug targets e.g. disease specific proteins, receptors, enzymes, genes. Each issue of the journal will be devoted to a single timely topic, with series of in-depth reviews, written by leaders in the field, covering a range of current topics on drug targets. These issues will be organized and led by a guest editor who is a recognized expert in the overall topic. As the discovery, identification, characterisation and validation of novel human drug targets for drug discovery continues to grow; this journal will be essential reading for all pharmaceutical scientists involved in drug discovery and development.

Publisher: Bentham Science Publishers

Volume 10, Number 2, February 2009

Articles

Targeted Tumor Therapies at a Glance
pp. 89-93(5)
Authors: Fuchs, H.; Bachran, C.

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Targeted Cancer Immunotherapy Using Ligands of the Tumor Necrosis Factor Super-Family
pp. 94-103(10)
Authors: Bremer, E.; de Bruyn, M.; Wajant, H.; Helfrich, W.

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Anti-CD3 Recombinant Diphtheria Immunotoxin Therapy of Cutaneous T Cell Lymphoma
pp. 104-109(6)
Authors: Frankel, A. E.; Zuckero, S. L.; Mankin, A. A.; Grable, M.; Mitchell, K.; Lee, Y. J.; Neville, D. M.; Woo, J. H.

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Anti-CD30 Human IL-2 Fusion Proteins Display Strong and Specific Cytotoxicity In Vivo
pp. 110-117(8)
Authors: Hirsch, B.; Brauer, J.; Fischdick, M.; Loddenkemper, C.; Bulfone-Paus, S.; Stein, H.; Durkop, H.

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Targeted Therapies for Prostate Cancer Against the Prostate Specific Membrane Antigen
pp. 118-125(8)
Authors: Elsasser-Beile, U.; Buhler, P.; Wolf, P.

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Convection-Enhanced Delivery: Neurosurgical Issues
pp. 126-130(5)
Author: Hall, W. A.

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Reducing the Immunogenicity of Protein Therapeutics
pp. 131-139(9)
Author: Onda, Masanori

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Saponins as Tool for Improved Targeted Tumor Therapies
pp. 140-151(12)
Authors: Fuchs, H.; Bachran, D.; Panjideh, H.; Schellmann, N.; Weng, A.; Melzig, M. F.; Sutherland, M.; Bachran, C.

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Targeting: The ADEPT Story So Far
pp. 152-157(6)
Author: Bagshawe, K. D.

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