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Current Drug Targets aims to cover the latest and most outstanding developments on the medicinal chemistry and pharmacology of molecular drug targets e.g. disease specific proteins, receptors, enzymes, genes. Each issue of the journal will be devoted to a single timely topic, with series of in-depth reviews, written by leaders in the field, covering a range of current topics on drug targets. These issues will be organized and led by a guest editor who is a recognized expert in the overall topic. As the discovery, identification, characterisation and validation of novel human drug targets for drug discovery continues to grow; this journal will be essential reading for all pharmaceutical scientists involved in drug discovery and development.

Publisher: Bentham Science Publishers

Volume 9, Number 8, August 2008

Articles

Cellular Membranes and Lipid-Binding Domains as Attractive Targets for Drug Development
pp. 603-613(11)
Authors: Sudhahar, C. G.; Haney, R. M.; Xue, Y.; Stahelin, R. V.

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The Life and Death of Protein Kinase C
pp. 614-625(12)
Authors: Gould, Christine M.; Newton, Alexandra C.

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Diacylglycerol Kinases as Emerging Potential Drug Targets for a Variety of Diseases
pp. 626-640(15)
Authors: Sakane, Fumio; Imai, Shin-ichi; Kai, Masahiro; Yasuda, Satoshi; Kanoh, Hideo

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Wealth of Opportunity - The C1 Domain as a Target for Drug Development
pp. 641-652(12)
Authors: Blumberg, P. M.; Kedei, N.; Lewin, N. E.; Yang, D.; Czifra, G.; Pu, Y.; Peach, M. L.; Marquez, V .E.

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Molecular Targeting of Acid Ceramidase: Implications to Cancer Therapy
pp. 653-661(9)
Authors: Zeidan, Youssef H.; Jenkins, Russell W.; Korman, John B.; Liu, Xiang; Obeid, Lina M.; Norris, James S.; Hannun, Yusuf A.

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Targeting SphK1 as a New Strategy against Cancer
pp. 662-673(12)
Authors: Shida, Dai; Takabe, Kazuaki; Kapitonov, Dmitri; Milstien, Sheldon; Spiegel, Sarah

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Ceramide Kinase and the Ceramide-1-Phosphate/cPLA2α Interaction as a Therapeutic Target
pp. 674-682(9)
Authors: Lamour, Nadia F.; Chalfant, Charles E.

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Therapeutic Potential of Autotaxin/Lysophospholipase D Inhibitors
pp. 698-708(11)
Authors: Federico, Lorenzo; Pamuklar, Zehra; Smyth, Susan S.; Morris, Andrew J.

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ENaC and Its Regulatory Proteins as Drug Targets for Blood Pressure Control
pp. 709-716(8)
Authors: Rotin, Daniela; Schild, Laurent

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