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Current Drug Targets aims to cover the latest and most outstanding developments on the medicinal chemistry and pharmacology of molecular drug targets e.g. disease specific proteins, receptors, enzymes, genes. Each issue of the journal will be devoted to a single timely topic, with series of in-depth reviews, written by leaders in the field, covering a range of current topics on drug targets. These issues will be organized and led by a guest editor who is a recognized expert in the overall topic. As the discovery, identification, characterisation and validation of novel human drug targets for drug discovery continues to grow; this journal will be essential reading for all pharmaceutical scientists involved in drug discovery and development.

Publisher: Bentham Science Publishers

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Volume 8, Number 6, June 2007

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Articles

Targeting the Leukemia Microenvironment
pp. 685-701(17)
Authors: Konopleva, Marina; Andreeff, Michael

FLT3 as a Therapeutic Target in Childhood Acute Leukemia
pp. 703-714(12)
Authors: Stubbs, Matthew C.; Armstrong, Scott A.

Targeting RAS Signaling Pathways in Juvenile Myelomonocytic Leukemia
pp. 715-725(11)
Authors: Flotho, Christian; Kratz, Christian; Niemeyer, Charlotte M.

Targeting Transcription Factors in Acute Leukemia in Children
pp. 727-737(11)
Authors: Berman, Jason N.; Thomas Look, A.

The Cytoskeleton as a Therapeutic Target in Childhood Acute Leukemia:Obstacles and Opportunities
pp. 739-749(11)
Authors: E. Liaw, Tracy Y.; Y. Chang, Melissa H.; Kavallaris, Maria

Microarray-Based Identification of New Targets for Specific Therapies in Pediatric Leukemia
pp. 761-764(4)
Authors: den Boer, Monique L.; Pieters, Rob

Assessing Combinations of Cytotoxic Agents Using Leukemia Cell Lines
pp. 765-771(7)
Authors: Patrick Reynolds, C.; Kang, Min H.; Keshelava, Nino; Maurer, Barry J.

In Vivo Models of Childhood Leukemia for Preclinical Drug Testing
pp. 773-783(11)
Authors: Bachmann, Petra S.; Lock, Richard B.

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