Current Drug Targets aims to cover the latest and most outstanding developments on the medicinal chemistry and pharmacology of molecular drug targets e.g. disease specific proteins, receptors, enzymes, genes. Each issue of the journal will be devoted to a single timely topic, with series of in-depth reviews, written by leaders in the field, covering a range of current topics on drug targets. These issues will be organized and led by a guest editor who is a recognized expert in the overall topic. As the discovery, identification, characterisation and validation of novel human drug targets for drug discovery continues to grow; this journal will be essential reading for all pharmaceutical scientists involved in drug discovery and development.

Publisher: Bentham Science Publishers

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Volume 7, Number 11, November 2006

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Articles

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Glycogen Synthase Kinase-3 - An Overview of An Over-Achieving Protein Kinase
pp. 1377-1388(12)
Authors: Kockeritz, Lisa; Doble, Bradley; Patel, Satish; Woodgett, James R.

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Multiple Roles for Glycogen Synthase Kinase-3 as a Drug Target in Alzheimer's Disease
pp. 1389-1397(9)
Authors: Huang, Hui-Chuan; Klein, Peter S.

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Targeting Glycogen Synthase Kinase-3 in the CNS: Implications for the Development of New Treatments for Mood Disorders
pp. 1399-1409(11)
Authors: Gould, Todd D.; Picchini, Alyssa M.; Einat, Haim; Manji, Husseini K.

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Free Content GSK3 at the Edge: Regulation of Developmental Specification and Cell Polarization
pp. 1411-1419(9)
Authors: Kim, Leung; Kimmel, Alan R.

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Glycogen Synthase Kinase-3 (GSK3) in Psychiatric Diseases and Therapeutic Interventions
pp. 1421-1434(14)
Authors: Jope, Richard S.; Roh, Myoung-Sun

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Role of Glycogen Synthase Kinase-3 in Insulin Resistance and Type 2 Diabetes
pp. 1435-1441(7)
Authors: Henriksen, Erik J.; Dokken, Betsy B.

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The Saccharomyces cerevisiae GSK-3β Homologs
pp. 1455-1465(11)
Authors: Kassir, Yona; Rubin-Bejerano, Ifat; Mandel- Gutfreund, Yael

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Editorial [Hot Topic: Ageing (Guest Editors: H.-P. Deigner and R. Kinscherf)]
pp. 1467-1468(2)
Authors: Deigner, Hans-Peter; Kinscherf, Ralf

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Foreseeable Pharmaceutical Repair of Age-Related Extracellular Damage
pp. 1469-1477(9)
Author: N.J. de Grey, Aubrey D.

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The Pharmacology of Ageing in Drosophila
pp. 1479-1483(5)
Authors: Jafari, Mahtab; Long, Anthony D.; Mueller, Laurence D.; Rose, Michael R.

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The Deficit in Low Molecular Weight Thiols as a Target for Antiageing Therapy
pp. 1505-1512(8)
Authors: Droge, Wulf; Kinscherf, Ralf; Hildebrandt, Wulf; Schmitt, Thomas

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Therapeutic Efficacy of Selegiline in Neurodegenerative Disorders and Neurological Diseases
pp. 1513-1529(17)
Authors: Ebadi, Manuchair; Brown-Borg, Holly; Ren, Jun; Sharma, Sushil; Shavali, Shaik; El ReFaey, Hesham; Carlson, Edward C.

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The Endocannabinoid System in Ageing: A New Target for Drug Development
pp. 1539-1552(14)
Authors: Paradisi, A.; Oddi, S.; Maccarrone

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The Role of NAD+ Dependent Histone Deacetylases (sirtuins) in Ageing
pp. 1553-1560(8)
Authors: Trapp, Johannes; Jung, Manfred

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