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Current Drug Targets aims to cover the latest and most outstanding developments on the medicinal chemistry and pharmacology of molecular drug targets e.g. disease specific proteins, receptors, enzymes, genes. Each issue of the journal will be devoted to a single timely topic, with series of in-depth reviews, written by leaders in the field, covering a range of current topics on drug targets. These issues will be organized and led by a guest editor who is a recognized expert in the overall topic. As the discovery, identification, characterisation and validation of novel human drug targets for drug discovery continues to grow; this journal will be essential reading for all pharmaceutical scientists involved in drug discovery and development.

Publisher: Bentham Science Publishers

Volume 6, Number 3, May 2005

Book review

Review article

The ErbB Receptors and their Ligands in Cancer: An Overview
pp. 243-257(15)
Authors: Normanno, N.; Bianco, C.; Strizzi, L.; Mancino, M.; Maiello, M. R.; Luca, A. D.; Caponigro, F.; Salomon, D. S.

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Small Molecules with EGFR-TK Inhibitor Activity
pp. 259-274(16)
Authors: Albanell, Joan; Gascon, Pere

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Monoclonal Antibodies Targeting the Epidermal Growth Factor Receptor
pp. 275-287(13)
Authors: Bianco, R.; Daniele, G.; Ciardiello, F.; Tortora, G.

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Antitumor Therapeutic Strategies Based on the Targeting of Epidermal Growth Factor-Induced Survival Pathways
pp. 289-300(12)
Authors: Tagliaferri, P.; Tassone, P.; Blotta, S.; Viscomi, C.; Grillone, F.; Budillon, A.; Caraglia, M.; Venuta, S.

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Isoprenylation of Intracellular Proteins as a New Target for the Therapy of Human Neoplasms: Preclinical and Clinical Implications
pp. 301-323(23)
Authors: Caraglia, M.; Budillon, A.; Tagliaferri, P.; Marra, M.; Abbruzzese, A.; Caponigro, F.

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Drugging Cell Cycle Kinases in Cancer Therapy
pp. 325-335(11)
Authors: Blagden, S.; Bono, J. d.

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Multiple-Target Drugs: Inhibitors of Heat Shock Protein 90 and of Histone Deacetylase
pp. 337-351(15)
Authors: Budillon, A.; Bruzzese, F.; Gennaro, E. D.; Caraglia, M.

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Colloidal Carriers for Ophthalmic Drug Delivery
pp. 363-371(9)
Authors: Mainardes, Rubiana M.; Urban, Maria C. C.; Cinto, Priscila Oliveira; Khalil, Najeh Maissar; Chaud, Marco Vinicius; Evangelista, Raul Cesar; Daflon Gremiao, Maria Palmira

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