Home >> Current Drug Targets, Volume 5, Number 8
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Current Drug Targets aims to cover the latest and most outstanding developments on the medicinal chemistry and pharmacology of molecular drug targets e.g. disease specific proteins, receptors, enzymes, genes. Each issue of the journal will be devoted to a single timely topic, with series of in-depth reviews, written by leaders in the field, covering a range of current topics on drug targets. These issues will be organized and led by a guest editor who is a recognized expert in the overall topic. As the discovery, identification, characterisation and validation of novel human drug targets for drug discovery continues to grow; this journal will be essential reading for all pharmaceutical scientists involved in drug discovery and development.

Publisher: Bentham Science Publishers

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Volume 5, Number 8, November 2004

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Book review

Editorial
pp. 665-666(2)
Authors: Mauro Magnani; Roberto Gambari; Rita Crinelli

Review article

Ribozyme- and Deoxyribozyme-Strategies for Medical Applications
pp. 667-681(15)
Authors: S. Schubert; J. Kurreck

Killing the Messenger: Antisense DNA and siRNA
pp. 683-689(7)
Authors: M. Nesterova; Y. S. Cho-Chung

Triplex-Forming Oligonucleotides - Sequence-Specific DNA Ligands as Tools for Gene Inhibition and for Modulation of DNA-Associated Functions
pp. 691-703(13)
Authors: Robert Besch; Carine Giovannangeli; Klaus Degitz

Progress in Thioaptamer Development
pp. 705-715(11)
Authors: Xianbin Yang; David G. Gorenstein

Application of Decoy Oligodeoxynucleotides-Based Approach to Renal Diseases
pp. 717-733(17)
Authors: Naruya Tomita; Haruhito Azuma; Yasufumi Kaneda; Toshio Ogihara; Ryuichi Morishita

Peptide Nucleic Acids (PNA)-DNA Chimeras Targeting Transcription Factors as a Tool to Modify Gene Expression
pp. 735-744(10)
Authors: M. Borgatti; A. Finotti; A. Romanelli; M. Saviano; N. Bianchi; I. Lampronti; E. Lambertini; L. Penolazzi; C. Nastruzzi; C. Mischiati; R. Piva; C. Pedone; R. Gambari

Locked Nucleic Acids (LNA): Versatile Tools for Designing Oligonucleotide Decoys with High Stability and Affinity
pp. 745-752(8)
Authors: R. Crinelli; M. Bianchi; L. Gentilini; L. Palma; M. Magnani

In Vivo Imaging of Oligonucleotides with Nuclear Tomography
pp. 753-760(8)
Author: Adriano Duatti

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