Pharmacokinetics of Biotech Drugs: Peptides, Proteins and Monoclonal Antibodies
Keywords: Asialoglycoprotein receptor; Clathrin-mediated and caveolae-mediated endocytosis; Endopeptidase and exopeptidase; Enhanced permeability and retention effect; Lymphatic absorption; Lysosomal degradation; Nanoparticulate delivery systems; Neonatal Fc receptor (FcRn); Receptor-mediated endocytosis; Ubinquitin protesome system
Document Type: Research Article
Publication date: 01 September 2009
- Current Drug Metabolism aims to cover all the latest and outstanding developments in drug metabolism and disposition. The journal serves as an international forum for the publication of timely reviews in drug metabolism. Current Drug Metabolism is an essential journal for academic, clinical, government and pharmaceutical scientists who wish to be kept informed and up-to-date with the latest and most important developments. The journal covers the following areas:
In vitro systems including CYP-450; enzyme induction and inhibition; drug-drug interactions and enzyme kinetics; pharmacokinetics, toxicokinetics, species scaling and extrapolations; P-glycoprotein and transport carriers; target organ toxicity and interindividual variability; drug metabolism and disposition studies; extrahepatic metabolism; phase I and phase II metabolism; recent developments for the identification of drug metabolites and adducts.