Home >> Current Drug Metabolism, Volume 9, Number 5
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Current Drug Metabolism aims to cover all the latest and outstanding developments in drug metabolism and disposition. The journal serves as an international forum for the publication of timely reviews in drug metabolism. Current Drug Metabolism is an essential journal for academic, clinical, government and pharmaceutical scientists who wish to be kept informed and up-to-date with the latest and most important developments. The journal covers the following areas:

In vitro systems including CYP-450; enzyme induction and inhibition; drug-drug interactions and enzyme kinetics; pharmacokinetics, toxicokinetics, species scaling and extrapolations; P-glycoprotein and transport carriers; target organ toxicity and interindividual variability; drug metabolism and disposition studies; extrahepatic metabolism; phase I and phase II metabolism; recent developments for the identification of drug metabolites and adducts.

Publisher: Bentham Science Publishers

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Volume 9, Number 5, June 2008

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Articles

Editorial
pp. 361-362(2)
Author: Prakash, Chandra

Molecular Characterization of CYP2B6 Substrates
pp. 363-373(11)
Authors: Ekins, Sean; Iyer, Manisha; Krasowski, Matthew D.; Kharasch, Evan D.

The Challenges of Dealing with Promiscuous Drug-Metabolizing Enzymes, Receptors and Transporters
pp. 374-383(10)
Authors: Ma, Qiang; Lu, Anthony Y.H.

Cytochrome P450 Turnover: Regulation of Synthesis and Degradation, Methods for Determining Rates, and Implications for the Prediction of Drug Interactions
pp. 384-393(10)
Authors: Yang, Jiansong; Liao, Mingxiang; Shou, Magang; Jamei, Masoud; Yeo, Karen R.; Tucker, Geoffrey T.; Rostami-Hodjegan, Amin

An Update on Clinical Drug Interactions with the Herbal Antidepressant St. John's wort
pp. 394-409(16)
Authors: Zhou, Shu-Feng; Lai, Xinsheng

Metabolism of Atypical Antipsychotics: Involvement of Cytochrome P450 Enzymes and Relevance for Drug-Drug Interactions
pp. 410-418(9)
Authors: Urichuk, Liana; Prior, Trevor I.; Dursun, Serdar; Baker, Glen

Applications and Limitations of Genetically Modified Mouse Models in Drug Discovery and Development
pp. 419-438(20)
Author: Lin, Jiunn H.

Liver-Enriched Transcription Factors and Their Role in Regulating UDP Glucuronosyltransferase Gene Expression
pp. 439-452(14)
Authors: Gardner-Stephen, D. A.; Mackenzie, P. I.

Heterotropic Cooperativity in Oxidation Mediated by Cytochrome P450
pp. 453-462(10)
Authors: Niwa, Toshiro; Murayama, Norie; Yamazaki, Hiroshi

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