Cytomics

Authors: Gomase, Virendra S.; Tagore, Somnath

Source: Current Drug Metabolism, Volume 9, Number 3, March 2008 , pp. 263-266(4)

Publisher: Bentham Science Publishers

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Abstract:

Cytomics is the branch of omics that takes into account the various bioinformatic techniques for understanding the functions and molecular architecture of the cytome. Cytomics, the multi-molecular cytometric analysis of the cellular heterogeneity of cytomes, access a maximum of information on the apparent molecular cell phenotype as it results from cell genotype and exposure. This has been done using various cytometrical procedures including microscopic techniques allowing the various components of a cell to be visualized as they interact in vivo.

Keywords: Cytome; heterogeneity; metabolome; phenotype; proteome

Document Type: Research article

DOI: http://dx.doi.org/10.2174/138920008783884731

Publication date: 2008-03-01

More about this publication?

Current Drug Metabolism aims to cover all the latest and outstanding developments in drug metabolism and disposition. The journal serves as an international forum for the publication of timely reviews in drug metabolism. Current Drug Metabolism is an essential journal for academic, clinical, government and pharmaceutical scientists who wish to be kept informed and up-to-date with the latest and most important developments. The journal covers the following areas:

In vitro systems including CYP-450; enzyme induction and inhibition; drug-drug interactions and enzyme kinetics; pharmacokinetics, toxicokinetics, species scaling and extrapolations; P-glycoprotein and transport carriers; target organ toxicity and interindividual variability; drug metabolism and disposition studies; extrahepatic metabolism; phase I and phase II metabolism; recent developments for the identification of drug metabolites and adducts.