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Current Drug Metabolism aims to cover all the latest and outstanding developments in drug metabolism and disposition. The journal serves as an international forum for the publication of timely reviews in drug metabolism. Current Drug Metabolism is an essential journal for academic, clinical, government and pharmaceutical scientists who wish to be kept informed and up-to-date with the latest and most important developments. The journal covers the following areas:

In vitro systems including CYP-450; enzyme induction and inhibition; drug-drug interactions and enzyme kinetics; pharmacokinetics, toxicokinetics, species scaling and extrapolations; P-glycoprotein and transport carriers; target organ toxicity and interindividual variability; drug metabolism and disposition studies; extrahepatic metabolism; phase I and phase II metabolism; recent developments for the identification of drug metabolites and adducts.

Publisher: Bentham Science Publishers

Volume 7, Number 6, August 2006
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Articles

Pharmacokinetics of Recombinant Human Endostatin in Rats
pp. 565-576(12)
Authors: Yang, Xiao-Xia; Hu, Zen-Ping; Chan, Eli; Duan, Wei; Zhou, Shufeng

Induction of Propranolol Metabolism by Ginkgo biloba Extract EGb 761 in Rats
pp. 577-587(11)
Authors: Zhao, Li-Zi; Huang, Ming; Chen, Jie; Rachel Ee, Pui Lai; Chan, Eli; Duan, Wei; Guan, Yong-Yuna; Hong, Yun-Han; Chen, Xiao; Zhou, Shufeng

Investigating Human P450s Involved in Drug Metabolism via Homology with High-Resolution P450 Crystal Structures of the CYP2C Subfamily
pp. 589-598(10)
Authors: Lewis, David F.V.; Ito, Yuko; Goldfarb, Peter S.

Antitumoral Activity of Interferon-γ Involved in Impaired Immune Function in Cancer Patients
pp. 599-612(14)
Authors: Brandacher, Gerald; Winkler, Christiana; Schroecksnadel, Katharina; Margreiter, Raimund; Fuchs, Dietmar

Relevance of the Deletion Polymorphisms of the Glutathione S-Transferases GSTT1 and GSTM1 in Pharmacology and Toxicology
pp. 613-628(16)
Authors: Bolt, H. M.; Thier, R.

Molecular Mechanisms Underlying the Dedifferentiation Process of Isolated Hepatocytes and Their Cultures
pp. 629-660(32)
Authors: Elaut, Greetje; Henkens, Tom; Papeleu, Peggy; Snykers, Sarah; Vinken, Mathieu; Vanhaecke, Tamara; Rogiers, Vera

Modulation of Metabolic Enzymes by Dietary Phytochemicals: A Review of Mechanisms Underlying Beneficial Versus Unfavorable Effects
pp. 661-675(15)
Authors: Mandlekar, Sandhya; Hong, Jin-Liern; Tony Kong, Ah-Ng

Thalidomide Metabolism and Hydrolysis: Mechanisms and Implications
pp. 677-685(9)
Authors: Lepper, Erin R.; Smith, Nicola F.; Cox, Michael C.; Scripture, Charity D.; Figg, William D.

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