Home >> Current Drug Metabolism, Volume 7, Number 2
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Current Drug Metabolism aims to cover all the latest and outstanding developments in drug metabolism and disposition. The journal serves as an international forum for the publication of timely reviews in drug metabolism. Current Drug Metabolism is an essential journal for academic, clinical, government and pharmaceutical scientists who wish to be kept informed and up-to-date with the latest and most important developments. The journal covers the following areas:

In vitro systems including CYP-450; enzyme induction and inhibition; drug-drug interactions and enzyme kinetics; pharmacokinetics, toxicokinetics, species scaling and extrapolations; P-glycoprotein and transport carriers; target organ toxicity and interindividual variability; drug metabolism and disposition studies; extrahepatic metabolism; phase I and phase II metabolism; recent developments for the identification of drug metabolites and adducts.

Publisher: Bentham Science Publishers

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Volume 7, Number 2, February 2006

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Articles

Induction of Cytochrome P450 3A4 and P-Glycoprotein by the Isoxazolyl- Penicillin Antibiotic Flucloxacillin
pp. 119-126(8)
Authors: Huwyler, Jorg; Wright, Matthew B.; Gutmann, Heike; Drewe, Juergen

Fluoxetine Metabolism and Pharmacological Interactions: The Role of Cytochrome P450
pp. 127-133(7)
Authors: Mandrioli, R.; Forti, G. C.; Raggi, M. A.

Prediction of Drug-Drug Interactions for AUCoral of High Clearance Drug from In Vitro Data: Utilization of a Microtiter Plate Assay and a Dispersion Model
pp. 135-146(12)
Authors: Yamamoto, Takahito; Suzuki, Akio; Kohno, Yoshiro; Nagata, Kiyoshi; Yamazoe, Yasushi

Predicting the Pharmacokinetics of Acyl Glucuronides and Their Parent Compounds in Disease States
pp. 147-163(17)
Authors: Liu, Jian H.; Smith, Philip C.

Preclinical Pharmacokinetics: An Approach Towards Safer and Efficacious Drugs
pp. 165-182(18)
Author: Singh, Sonu S.

The Role of Blood-Brain Barrier Studies in the Pharmaceutical Industry
pp. 183-203(21)
Author: Reichel, Andreas

Recent Advances in Molecular Modeling and Medicinal Chemistry Aspects of Phospho-Glycoprotein#
pp. 205-217(13)
Authors: Srinivas, E.; Murthy, J. N.; Rao, A. R.R.; Sastry, G. N.

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