Home >> Current Drug Metabolism, Volume 6, Number 5
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Current Drug Metabolism aims to cover all the latest and outstanding developments in drug metabolism and disposition. The journal serves as an international forum for the publication of timely reviews in drug metabolism. Current Drug Metabolism is an essential journal for academic, clinical, government and pharmaceutical scientists who wish to be kept informed and up-to-date with the latest and most important developments. The journal covers the following areas:

In vitro systems including CYP-450; enzyme induction and inhibition; drug-drug interactions and enzyme kinetics; pharmacokinetics, toxicokinetics, species scaling and extrapolations; P-glycoprotein and transport carriers; target organ toxicity and interindividual variability; drug metabolism and disposition studies; extrahepatic metabolism; phase I and phase II metabolism; recent developments for the identification of drug metabolites and adducts.

Publisher: Bentham Science Publishers

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Volume 6, Number 5, October 2005

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Review article

Effect of Omeprazole on the Hydroxylation of Warfarin Enantiomers in Human: In-Vitro Studies with Liver Microsomes and cDNA-Expressed Cytochrome P450 Isozymes
pp. 399-411(13)
Authors: Zhou, Q.; Zhou, S.; Chan, E.

Cytochrome P450 Enzymes Mechanism Based Inhibitors: Common Sub-Structures and Reactivity
pp. 413-451(39)
Authors: Fontana, E.; Dansette, P. M.; Poli, S. M.

Coupling of Conjugating Enzymes and Efflux Transporters: Impact on Bioavailability and Drug Interactions
pp. 455-468(14)
Authors: Jeong, E. J.; Liu, X.; Jia, X.; Chen, J.; Hu, M.

CYP1A1 Is a Major Enzyme Responsible for the Metabolism of Granisetron in Human Liver Microsomes
pp. 469-480(12)
Authors: Nakamura, H.; Ariyoshi, N.; Okada, K.; Nakasa, H.; Nakazawa, K.; Kitada, M.

Effect of Some Biologically Interesting Substituted Tetrahydro-1,4- Oxazines on Drug Metabolising Enzymes and on Inflammation
pp. 481-485(5)
Authors: Rekka, E. A.; Kourounakis, A. P.; Avramidis, N.; Kourounakis, P. N.

Metabolism and Disposition of the Antiviral Nucleoside Analogue AM365 in the Isolated Perfused Rat Liver
pp. 487-493(7)
Authors: Wang, J.; Nation, R. L.; Evans, A. M.; Cox, S.; Shackleford, D.

Mechanisms of Male Infertility: Role of Antioxidants
pp. 495-501(7)
Authors: Sheweita, S. A.; Tilmisany, A. M.; Al-Sawaf, H.

Utility of Recombinant Cytochrome P450 Enzymes: A Drug Metabolism Perspective
pp. 503-517(15)
Authors: Tang, W.; Wang, R. W.; Lu, Anthony Y.H.

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