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Microsponge Delivery System
Authors: Chadawar, Vikrant; Shaji, Jessy
Source: Current Drug Delivery, Volume 4, Number 2, April 2007 , pp. 123-129(7)
Publisher: Bentham Science Publishers
Abstract:
Microsponges are polymeric delivery systems consisting of porous microspheres having a size range in between 5 to 300 μm depending upon the degree of smoothness or after feel required for the end formulations. Microsponge Delivery System MDS is a unique technology for controlled delivery of drug. The present review introduces Microsponge technology along with its synthesis, characterization, programmable parameters and release mechanism of MDS. Wide ranges of applications are also suggested to develop drug or cosmetic products with enhanced safety and efficacy. MDS can provide increased efficacy for topically active agents with enhanced safety, extended product stability and improved aesthetic properties in an efficient and novel manner.Keywords: Microsponge; quasi emulsion diffusion solvent method; free radical suspension polymerization; porous microsphere; release mechanism
Document Type: Research article
DOI: http://dx.doi.org/10.2174/156720107780362320
Affiliations: 1: Dept. of Pharmaceutics, Prin.K.M.Kundnani College of Pharmacy, Plot No. 23, Jote Joy Building, Cuffe Parade, Colaba, Mumbai- 400 005,India.
Publication date: 2007-04-01
- The aim of Current Drug Delivery is to publish peer-reviewed articles, short communications, short and in-depth reviews in the rapidly developing field of drug delivery. Modern drug research aims to build in delivery properties of a drug at the design phase, however in many cases this ideal cannot be met and the development of delivery systems becomes as important as the development as the drugs themselves.
The journal aims to cover the latest outstanding developments in drug and vaccine delivery employing physical, physico-chemical and chemical methods. The drugs include a wide range of bioactive compounds from simple pharmaceuticals to peptides, proteins, nucleotides, nucleosides and sugars. The journal will also report progress in the fields of transport routes and mechanisms including efflux proteins and multi-drug resistance.
The journal is essential for all pharmaceutical scientists involved in drug design, development and delivery.
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- In this Subject: Pharmacology
- By this author: Chadawar, Vikrant ; Shaji, Jessy
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