IngentaConnect Microsponge Delivery System

Authors: Chadawar, Vikrant¹; Shaji, Jessy¹

Source: Current Drug Delivery, Volume 4, Number 2, April 2007 , pp. 123-129(7)

Publisher: Bentham Science Publishers

Abstract:

Microsponges are polymeric delivery systems consisting of porous microspheres having a size range in between 5 to 300 μm depending upon the degree of smoothness or after feel required for the end formulations. Microsponge Delivery System MDS is a unique technology for controlled delivery of drug.

The present review introduces Microsponge technology along with its synthesis, characterization, programmable parameters and release mechanism of MDS. Wide ranges of applications are also suggested to develop drug or cosmetic products with enhanced safety and efficacy. MDS can provide increased efficacy for topically active agents with enhanced safety, extended product stability and improved aesthetic properties in an efficient and novel manner.

Keywords: Microsponge; quasi emulsion diffusion solvent method; free radical suspension polymerization; porous microsphere; release mechanism

Document Type: Research article

DOI: 10.2174/156720107780362320

Affiliations: 1: Dept. of Pharmaceutics, Prin.K.M.Kundnani College of Pharmacy, Plot No. 23, Jote Joy Building, Cuffe Parade, Colaba, Mumbai- 400 005,India.

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