Skip to main content

Overlaps in the Nosology of Substance Abuse and Overeating: The Translational Implications of “Food Addiction”

Buy Article:

$55.00 plus tax (Refund Policy)

The obesity epidemic has led to the postulation that highly palatable foods may be “addictive” for some individuals. This idea is supported by the fact that there are overlaps in brain circuitry that underlie addictive behavior as well as overeating. In this paper, we discuss the utility of the concept of “food addiction” as it may relate to treating certain disordered eating behaviors. Using criteria set forth in the DSM-IV for substance-use disorders, we review data that have emerged from animal models suggesting that overeating, in the form of binge eating, fits some of the criteria for substance abuse. Further, we discuss preclinical data revealing that the addiction-like behavioral changes observed in response to overeating are concomitant with neurochemical changes that are similar to those observed in response to drugs of abuse. With this background and evidence in mind, we conclude this article with a discussion as to how “food addiction” research may translate into clinical strategies and pharmaceutical treatments useful in curtailing overeating.





No References
No Citations
No Supplementary Data
No Data/Media
No Metrics

Keywords: Addiction; Binge eating; Dependence; Dopamine; Hyperpalatable food; food addiction; obesity; overeating; rat; translational research

Document Type: Research Article

Publication date: 2011-09-01

More about this publication?
  • Current Drug Abuse Reviews aims to publish the highest quality reviews, meta-analyses and drug clinical trial studies on all latest advances on alcohol and drug abuse and addiction.

    Book reviews are also published. The Journal will further comprise an agenda listing relevant meetings and conferences that will take place in near future, and advertisement.

  • Editorial Board
  • Information for Authors
  • Subscribe to this Title
  • Ingenta Connect is not responsible for the content or availability of external websites
  • Access Key
  • Free content
  • Partial Free content
  • New content
  • Open access content
  • Partial Open access content
  • Subscribed content
  • Partial Subscribed content
  • Free trial content
Cookie Policy
X
Cookie Policy
Ingenta Connect website makes use of cookies so as to keep track of data that you have filled in. I am Happy with this Find out more