Skip to main content

HPV Vaccination in Adolescents: From Clinical Data to Implementation and Practice

Buy Article:

$55.00 plus tax (Refund Policy)

Persistent human Papillomavirus (HPV) infections are now recognised as the leading cause of cervical cancer (CC).

Approximately 100 types of human infecting HPV exist in nature and according to the samples collected from either pre-cancerous or cancerous lesions, almost ten are responsible for a good part of the CC cases. Two anti-HPV vaccines are currently registered worldwide - a tetravalent and a bivalent one - for which evidences of protecting effectiveness and safety have been delivered by controlled clinical trials and clinical practice. Consequently, and as a first step, several countries implemented HPV mass vaccination programmes for girls before the age of sexual debut. Moreover, and specifically for the bivalent vaccine, efficacy over various oncogenic types has been demonstrated in a broad population also including sexually active women that had potentially already acquired an HPV infection. The opportunity to extend the primary prevention to other cohorts of women up to the adult age through the use of the vaccine, improves the possibility to actively reduce the total number of CC cases. Based on two country examples, Italy and Belgium, different strategies for HPV vaccination of pre-adolescents, adolescents and young adults are discussed.

No References
No Citations
No Supplementary Data
No Article Media
No Metrics

Keywords: Papillomavirus; adolescents; anti-HPV vaccines; immunogenic effects; pre-adolescents; primary prevention; young adults

Document Type: Research Article

Publication date: 2010-05-01

More about this publication?
  • Current Cancer Therapy Reviews publishes frontier reviews on all the latest advances in clinical oncology, cancer therapy and pharmacology. The journal's aim is to publish the highest quality review articles dedicated to clinical research in the field. The journal is essential reading for all researchers and clinicians in cancer therapy.
  • Access Key
  • Free content
  • Partial Free content
  • New content
  • Open access content
  • Partial Open access content
  • Subscribed content
  • Partial Subscribed content
  • Free trial content
Cookie Policy
Cookie Policy
Ingenta Connect website makes use of cookies so as to keep track of data that you have filled in. I am Happy with this Find out more