Triglycerides and Cardiovascular Risk

Authors: Harchaoui, K. E.L.; Visser, M. E.; Kastelein, J. J.P.; Stroes, E. S.; Dallinga-Thie, G. M.

Source: Current Cardiology Reviews, Volume 5, Number 3, August 2009 , pp. 216-222(7)

Publisher: Bentham Science Publishers

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Abstract:

In 1996 a meta-analysis was published showing that an increase in plasma triglyceride (TG) levels was associated with an increase in CHD risk, even after adjustment for high density lipoprotein cholesterol (HDL-C) levels. Very recently, two studies were published that further extent the early observation and showed the importance of nonfasting plasma triglyceride (TG) levels in the prediction of risk on coronary heart disease (CHD). In the current review we have summarized all available evidence obtained in clinical studies showing that treatment guidelines should reconsider to include nonfasting TG in their risk assessments as nonfasting TG levels may better predict CVD risk.

Keywords: Triglycerides; coronary heart disease; lipoproteins; lipolytic enzymes

Document Type: Research article

DOI: http://dx.doi.org/10.2174/157340309788970315

Publication date: 2009-08-01

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Current Cardiology Reviews publishes frontier reviews on all the latest advances on the practical and clinical approach to the diagnosis and treatment of cardiovascular disease. All relevant areas are covered by the journal including arrhythmia, congestive heart failure, cardiomyopathy, congenital heart disease, drugs, methodology, pacing, and preventive cardiology. The journal's aim is to publish the highest quality review articles dedicated to clinical research in the field. The journal is essential reading for all researchers and clinicians in cardiology.