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Combinatorial Chemistry & High Throughput Screening publishes full length original research articles and reviews describing various topics in combinatorial chemistry (e.g. small molecules, peptide, nucleic acid or phage display libraries) and/or high throughput screening (e.g. developmental, practical or theoretical). Ancillary subjects of key importance, such as robotics and informatics, will also be covered by the journal. In these respective subject areas, Combinatorial Chemistry & High Throughput Screening is intended to function as the most comprehensive and up-to-date medium available. The journal should be of value to individuals engaged in the process of drug discoveryand development, in the settings of industry, academia or government.

Publisher: Bentham Science Publishers

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Volume 8, Number 8, December 2005

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Book review

Review article

Genome Projects and the Functional-Genomic Era
pp. 659-667(9)
Authors: Sauer, Sascha; Konthur, Zoltan; Lehrach, Hans

Gel-Based Versus Gel-Free Proteomics: A Review
pp. 669-677(9)
Authors: Baggerman, Geert; Vierstraete, Evy; De Loof, Arnold; Schoofs, Liliane

Proteomics in Nutrition and Health
pp. 679-696(18)
Authors: Kussmann, Martin; Affolter, Michael; Fay, Laurent B.

The Peptidomics Concept
pp. 697-704(8)
Authors: Schulz-Knappe, Peter; Schrader, Michael; Zucht, Hans-Dieter

Bioinformatics Challenges in Proteomics
pp. 705-715(11)
Authors: Englbrecht, Claudia C.; Facius, Axel

Datamining Methodology for LC-MALDI-MS Based Peptide Profiling
pp. 717-723(7)
Authors: Zucht, Hans-Dieter; Lamerz, Jens; Khamenia, Valery; Schiller, Carsten; Appel, Annette; Tammen, Harald; Crameri, Reto; Selle, Hartmut

Prerequisites for Peptidomic Analysis of Blood Samples: I. Evaluation of Blood Specimen Qualities and Determination of Technical Performance Characteristics
pp. 725-733(9)
Authors: Tammen, Harald; Schulte, Imke; Hess, Rudiger; Menzel, Christoph; Kellmann, Markus; Schulz-Knappe, Peter

Prerequisites for Peptidomic Analysis of Blood Samples: II. Analysis of Human Plasma after Oral Glucose Challenge - A Proof of Concept
pp. 735-741(7)
Authors: Tammen, Harald; Hess, Rudiger; Schulte, Imke; Kellmann, Markus; Appel, Annette; Budde, Petra; Zucht, Hans-Dieter; Schulz-Knappe, Peter

High-Throughput Biomarker Discovery and Identification by Mass Spectrometry
pp. 743-755(13)
Authors: Menzel, Christoph; Guillou, Vincent; Kellmann, Markus; Khamenya, Valery; Juergens, Michael; Schulz-Knappe, Peter

Towards Characterization of the Human Urinary Peptidome
pp. 757-765(9)
Authors: Jurgens, Michael; Appel, Annette; Heine, Gabriele; Neitz, Susanne; Menzel, Christoph; Tammen, Harald; Zucht, Hans-Dieter

The Concept of Functional Peptidomics for the Discovery of Bioactive Peptides in Cell Culture Models
pp. 767-773(7)
Authors: Jost, Marco M.; Budde, Petra; Tammen, Harald; Hess, Rudiger; Kellmann, Markus; Schulte, Imke; Rose, Horst

Peptidomics Biomarker Discovery in Mouse Models of Obesity and Type 2 Diabetes
pp. 775-781(7)
Authors: Budde, Petra; Schulte, Imke; Appel, Annette; Neitz, Susanne; Kellmann, Markus; Tammen, Harald; Hess, Rudiger; Rose, Horst

Identification of Peptide Tumor Markers in a Tumor Graft Model in Immunodeficient Mice
pp. 783-788(6)
Authors: Tammen, Harald; Schorn, Karl; Selle, Hartmut; Hess, Rudiger; Neitz, Susanne; Reiter, Rudolf; Schulz-Knappe, Peter

Peptide Sequence Prediction Supported by Correlation-Associated Networks in Human Cerebrospinal Fluid
pp. 789-799(11)
Authors: Lamerz, Jens; Crameri, Reto; Scapozza, Leonardo; Mohring, Thomas; Selle, Hartmut; Zucht, Hans-Dieter

Identification of Novel Biomarker Candidates by Differential Peptidomics Analysis of Cerebrospinal Fluid in Alzheimer's Disease
pp. 801-806(6)
Authors: Selle, Hartmut; Lamerz, Jens; Buerger, Katharina; Dessauer, Andreas; Hager, Klaus; Hampel, Harald; Karl, Johann; Kellmann, Markus; Lannfelt, Lars; Louhija, Jukka; Riepe, Matthias; Rollinger, Wolfgang; Tumani, Hayrettin; Schrader, Michael; Zucht, Hans-Dieter

The Future of Post-Genomic Biology at the Proteomic Level: An Outlook
pp. 807-810(4)
Authors: Crameri, Reto; Schulz-Knappe, Peter; Zucht, Hans-Dieter

Meet the Guest Editor
pp. 811-811(1)
Author: Crameri, Reto

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