Synthesis of Trifluoromethyl Ketones Using Polymer-Supported Reagents
Authors: Baxendale I.R.; Ley S.V.; Lumeras W.; Nesi M.
Source: Combinatorial Chemistry & High Throughput Screening, Volume 5, Number 3, May 2002 , pp. 197-199(3)
Publisher: Bentham Science Publishers
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Abstract:
A two step synthesis of trifluoromethyl ketones from aldehydes is reported. A combination of polymer-supported reagents and sequestering agents were employed to effect the transformation without the need for chromatographic purification.
Keywords: polymer-supported reagent; sequestering agent; multi-parallel synthesis
Language: English
Document Type: Review article
DOI: 10.2174/1386207024607220
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