Solid Phase Synthesis of Structurally Diverse Tetra Substituted Pyrimidines for Potential Use in Combinatorial Chemistry

Authors: Chauhan P.M.S.; Kumar A.

Source: Combinatorial Chemistry & High Throughput Screening, Volume 5, Number 1, February 2002 , pp. 93-95(3)

Publisher: Bentham Science Publishers

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Abstract:

A new pyrimidine based scaffold has been identified for generation of combinatorial libraries using solid phase technique.The utility of the scaffolds was demonstrated by synthesizing small libraries of 12 substituted pyrimidines (4a-4l).

Keywords: Tetra Substituted Pyrimidines; Combinatorial Chemistry; solid phase technique

Language: English

Document Type: Review article

DOI: 10.2174/1386207023330525

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