Rapid Determination of Pharmacokinetic Properties of New Chemical Entities: In vivo Approaches
Authors: Cox K.A.; White R.E.; Korfmacher W.A.
Source: Combinatorial Chemistry & High Throughput Screening, Volume 5, Number 1, February 2002 , pp. 29-37(10)
Publisher: Bentham Science Publishers
Abstract:
There is a continuing need for increased throughput in the evaluation of new chemical entities in terms of their pharmacokinetic (PK) parameters as part of new drug discovery. This review summarizes various approaches that have been used to increase throughput in this area. The article divides the approaches into two areas: assay enhancement and sample reduction.
Keywords: Pharmacokinetic pk; drug discovery; solid phase extraction spe
Language: English
Document Type: Review article
DOI: http://dx.doi.org/10.2174/1386207023330534
Publication date: 2002-02-01
- Combinatorial Chemistry & High Throughput Screening publishes full length original research articles and reviews describing various topics in combinatorial chemistry (e.g. small molecules, peptide, nucleic acid or phage display libraries) and/or high throughput screening (e.g. developmental, practical or theoretical). Ancillary subjects of key importance, such as robotics and informatics, will also be covered by the journal. In these respective subject areas, Combinatorial Chemistry & High Throughput Screening is intended to function as the most comprehensive and up-to-date medium available. The journal should be of value to individuals engaged in the process of drug discoveryand development, in the settings of industry, academia or government.
- In this: publication
- By this: publisher
- In this Subject: Pharmacology
- By this author: Cox K.A. ; White R.E. ; Korfmacher W.A.

Shopping cart
Receive new issue alert
Get Permissions