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Combinatorial Chemistry & High Throughput Screening publishes full length original research articles and reviews describing various topics in combinatorial chemistry (e.g. small molecules, peptide, nucleic acid or phage display libraries) and/or high throughput screening (e.g. developmental, practical or theoretical). Ancillary subjects of key importance, such as robotics and informatics, will also be covered by the journal. In these respective subject areas, Combinatorial Chemistry & High Throughput Screening is intended to function as the most comprehensive and up-to-date medium available. The journal should be of value to individuals engaged in the process of drug discoveryand development, in the settings of industry, academia or government.

Publisher: Bentham Science Publishers

Volume 5, Number 1, February 2002
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Book Reviews

Preface
pp. i-i(1)
Author: van Breemen R.B.

Reviews

Random Sequence Libraries Displayed on Phage: Identification of Biologically Important Molecules
pp. 1-14(14)
Authors: Adda C.G.; Anders R.F.; Tilley L.; Foley M.

Mimotopes of Viral Antigens and Biologically Important Molecules as Candidate Vaccines and Potential Immunotherapeutics
pp. 15-27(13)
Authors: Partidos C.D.; Steward M.W.

Rapid Determination of Pharmacokinetic Properties of New Chemical Entities: In vivo Approaches
pp. 29-37(10)
Authors: Cox K.A.; White R.E.; Korfmacher W.A.

A Systematic SAR Study of C10 Modified Paclitaxel Analogues Using a Combinatorial Approach
pp. 39-48(8)
Authors: Liu Y.; Ali S.M.; Boge T.C.; Georg G.I.; Victory S.; Zygmunt J.; Marquez R.T.; Himes R.H.

Molecular Diversity Sample Generation on the Basis of Quantum-Mechanical Computations and Principal Component Analysis
pp. 49-57(9)
Authors: Gutierrez-de-Teran H.; Lozano J.J.; Segarra V.; Sanz F.

Screening Drugs for Metabolic Stability Using Pulsed Ultrafiltration Mass Spectrometry
pp. 59-64(5)
Authors: Shin Y.Geun; Bolton J.L.; Van Breemen R.B.

Evaluation of a Micro Volume Pulsed Ultrafiltration Cell for Screening Ligands in Non-Covalent Complexes
pp. 65-73(9)
Authors: Beverly M.B.; West P.; Julian R.K.

Solid-Phase and Solution-Phase Parallel Synthesis of Tetrahydro-isoquinolines via Pictet-Spengler Reaction
pp. 75-81(3)
Authors: Sun Q.; Kyle D.J.

Recognition of Multiple Substrate Motifs by the c-ABL Protein Tyrosine Kinase
pp. 83-91(10)
Authors: Wu J.J.; Afar D.E.H.; Phan H.; Witte O.N.; Lam K.S.

Solid Phase Synthesis of Structurally Diverse Tetra Substituted Pyrimidines for Potential Use in Combinatorial Chemistry
pp. 93-95(3)
Authors: Chauhan P.M.S.; Kumar A.

Addenda

Author Index To Volume 4
pp. 97-99(3)
Author: Bentham S.Publishers

subject Index To Volume 4
pp. 101-103(3)
Author: Bentham S.Publishers

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Key:
Free Content - Free Content
New Content - New Content
Subscribed Content - Subscribed Content
Free Trial Content - Free Trial Content
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