Dynamic Combinatorial Chemistry

Authors: Huc I.; Nguyen R.

Source: Combinatorial Chemistry & High Throughput Screening, Volume 4, Number 1, February 2001 , pp. 53-74(22)

Publisher: Bentham Science Publishers

Key:

- Free Content

- New Content

- Subscribed Content

- Free Trial Content

Abstract:

Dynamic combinatorial chemistry is based on the reversible combination of initial building blocks to form dynamic combinatorial libraries. It has recently emerged as an efficient strategy to detect and to evaluate affinity between the library products and a target molecule. In this review, examples from various fields of chemistry and biochemistry are presented and extensively discussed. The last section deals with the practical aspects for implementing this approach.

Keywords: Dynamic Combinatorial; potential diversity; dynamic generation; Si NMR; polycyclic oligomers; rational equilibiria; intramollecular forces; oligoamide 2

Language: English

Document Type: Review article

DOI: 10.2174/1386207013331273

The full text electronic article is available for purchase. You will be able to download the full text electronic article after payment.

$55.10 plus tax Refund Policy