A Merger of Rational Drug Design and Combinatorial Chemistry Development and Application of Peptide Secondary Structure Mimetics

Authors: Kim H-O.; Kahn M.

Source: Combinatorial Chemistry & High Throughput Screening, Volume 3, Number 3, June 2000 , pp. 167-183(17)

Publisher: Bentham Science Publishers

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Abstract:

Recent efforts toward the development of peptide secondary structure mimetics at Molecumetics Ltd. for the discoveries of new drug candidates utilizing combinatorial chemistry with solid phase synthesis are described.

Keywords: Drug design; Combinatorial Chemistry; Peptide secondary structure mimetis; Proteases; Cytokines

Language: English

Document Type: Review article

DOI: 10.2174/1386207003331625

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