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Current Cancer Drug Targets aims to cover all the latest and outstanding developments on the medicinal chemistry, pharmacology, molecular biology, genomics and biochemistry of contemporary molecular drug targets involved in cancer, e.g. disease specific proteins, receptors, enzymes, genes.
Each issue of the journal contains a series of timely in-depth reviews written by leaders in the field covering a range of current topics on drug targets involved in cancer.
As the discovery, identification, characterization and validation of novel human drug targets for anti-cancer drug discovery continues to grow; this journal has become essential reading for all pharmaceutical scientists involved in drug discovery and development.

Publisher: Bentham Science Publishers

Volume 12, Number 1, January 2012

Articles

Identification of Disease-Relevant Genes for Molecularly-Targeted Drug Discovery
pp. 1-13(13)
Authors: Kauselmann, G.; Dopazo, A.; Link, W.

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Nuclear Hormone Receptor Signals as New Therapeutic Targets for Urothelial Carcinoma
pp. 14-22(9)
Authors: Miyamoto, H.; Zheng, Y.; Izumi, K.

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The Critical Role of Vascular Endothelial Growth Factor in Tumor Angiogenesis
pp. 23-43(21)
Authors: Amini, A.; Masoumi Moghaddam, S.; L. Morris, D.; H. Pourgholami, M.

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Presence of Intratumoral Stem Cells in Breast Cancer Patients with or without BRCA Germline Mutations
pp. 44-50(7)
Authors: F. Singer, C.; Zabkova, P.; Rappaport, C.; Muhr, D.; Pfeiler, G.; Gschwantler-Kaulich, D.; Fink-Retter, A.; Staudigl, C.; Walter, I.; Hudelist, G.; Spiess, A.-C.; Kubista, E.

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The Hsp32 Inhibitors SMA-ZnPP and PEG-ZnPP Exert Major Growth-Inhibitory Effects on D34+/CD38+ and CD34+/CD38- AML Progenitor Cells
pp. 51-63(13)
Authors: Herrmann, H.; Kneidinger, M.; Cerny-Reiterer, S.; Rulicke, T.; Willmann, M.; V. Gleixner, K.; Blatt, K.; Hormann, G.; Peter, B.; Samorapoompichit, P.; Pickl, W.; Y. Bharate, G.; Mayerhofer, M.; R. Sperr, W.; Maeda, H.; Valent, P.

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Targeting Urokinase and the Transferrin Receptor with Novel, Anti-Mitotic N-Alkylisatin Cytotoxin Conjugates Causes Selective Cancer Cell Death and Reduces Tumor Growth
pp. 64-73(10)
Authors: L. Vine, K.; Indira Chandran, V.; M. Locke, J.; Matesic, L.; Lee, J.; Skropeta, D.; B. Bremner, J.; Ranson, M.

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Knockdown of Insulin-Like Growth Factor I Receptor Inhibits the Growth and Enhances Chemo-Sensitivity of Liver Cancer Cells
pp. 74-84(11)
Authors: Zhang, Y.-W.; Yan, D.-L.; Wang, W.; Zhao, H.-W.; Lu, X.; Wu, J.-Z.; Zhou, J.-R.

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