Skip to main content

Silica Nanoparticles as Promising Drug/Gene Delivery Carriers and Fluorescent Nano-Probes: Recent Advances

Buy Article:

$63.00 plus tax (Refund Policy)


The application of nanotechnology to biomedical research is expected to have a major impact leading to the development of new types of diagnostic and therapeutic tools. One focus in nanobiotechnology is to develop safe and efficient drug/gene delivery vehicles. Research into the rational delivery and targeting of pharmaceutical, therapeutic and diagnostic agents is at the forefront of projects in nanomedicine. Silica, as a major and natural component of sand and glass, is a versatile material due to the variety of available chemical and physical modifications that are available, and recently have been widely applied in nanobiotechnology as drug/gene carriers or fluorescent nano-probes. The goal of this brief review is to illustrate selected examples of various functionalized silica nanoparticles as drug/gene delivery systems that have been applied to the arenas of human disease therapy or detection (molecular and cellular imaging).

Keywords: 2-devinyl-2-(1-hexyloxyethyl) pyropheo-phorbide; DNA microarray; Folic acid; Silica; adenocarcinoma; antisense oligonucleotides; apoptosis; bromodeoxyuridine; cytoskeleton; drug/gene delivery; electrostatic interaction; fluorescein isothiocyanate; fluorescent dye; glutaraldehyde; immu-nocytochemistry; immunohistochemistry; immunosorbent assay; liposomes; luminescent; mesenchymal stem cells; mesoporous channels; mesoporous silica nanoparticles; nano-probes; nanobiotechnology; nanoparticles; nanotechnology; perfluorocarbon; photodynamic drugs; pituitary adenoma; plasmid DNA; polyethylene glycol; proliferation; sodium cyanide; sol-gel; stereotaxic injections; superparamagnetic iron ox-ide; superparamagnetic iron oxide; targeting; tetraethoxysilane; thiol-organosilica

Document Type: Research Article

Publication date: 2011-02-01

More about this publication?
  • Current Cancer Drug Targets aims to cover all the latest and outstanding developments on the medicinal chemistry, pharmacology, molecular biology, genomics and biochemistry of contemporary molecular drug targets involved in cancer, e.g. disease specific proteins, receptors, enzymes, genes.
    Each issue of the journal contains a series of timely in-depth reviews written by leaders in the field covering a range of current topics on drug targets involved in cancer.
    As the discovery, identification, characterization and validation of novel human drug targets for anti-cancer drug discovery continues to grow; this journal has become essential reading for all pharmaceutical scientists involved in drug discovery and development.
  • Access Key
  • Free content
  • Partial Free content
  • New content
  • Open access content
  • Partial Open access content
  • Subscribed content
  • Partial Subscribed content
  • Free trial content
Cookie Policy
Cookie Policy
Ingenta Connect website makes use of cookies so as to keep track of data that you have filled in. I am Happy with this Find out more