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Current Cancer Drug Targets aims to cover all the latest and outstanding developments on the medicinal chemistry, pharmacology, molecular biology, genomics and biochemistry of contemporary molecular drug targets involved in cancer, e.g. disease specific proteins, receptors, enzymes, genes.
Each issue of the journal contains a series of timely in-depth reviews written by leaders in the field covering a range of current topics on drug targets involved in cancer.
As the discovery, identification, characterization and validation of novel human drug targets for anti-cancer drug discovery continues to grow; this journal has become essential reading for all pharmaceutical scientists involved in drug discovery and development.

Publisher: Bentham Science Publishers

Volume 10, Number 8, December 2010

Articles

Predictive Molecular Markers of Response to Epidermal Growth Factor Receptor(EGFR) Family-Targeted Therapies
pp. 799-812(14)
Authors: Barton, Sarah; Starling, Naureen; Swanton, Charles

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KRAS Mutation Testing of Colorectal Cancer for Anti-EGFR Therapy: Dogmas Versus Evidence
pp. 813-823(11)
Authors: Timar, J.; Hegedus, B.; Raso, E.

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RAS Pathways in Prostate Cancer - Mediators of Hormone Resistance?
pp. 834-839(6)
Authors: C. Whitaker, H.; E. Neal, D.

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The Crosstalk of RAS with the TGF-β Family During Carcinoma Progression and its Implications for Targeted Cancer Therapy
pp. 849-857(9)
Authors: Grusch, M.; Petz, M.; Metzner, T.; Ozturk, D.; Schneller, D.; Mikulits, W.

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Biomarkers Downstream of RAS: A Search for Robust Transcriptional Targets
pp. 858-868(11)
Authors: Gyorffy, B.; Schafer, R.

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Ras-Induced Senescence and its Physiological Relevance in Cancer
pp. 869-876(8)
Authors: DiMauro, T.; David, G.

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Anti-Angiogenic Therapies for Children with Cancer
pp. 879-889(11)
Authors: Andre, N.; Verschuur, A.; Rossler, J.; Sterba, J.

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Histone Deacetylases: Anti-Angiogenic Targets in Cancer Therapy
pp. 898-913(16)
Authors: Mottet, D.; Castronovo, V.

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Endothelial Progenitor Cells: Hope Beyond Controversy
pp. 914-921(8)
Authors: Pasquier, E.; Dias, S.

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Inhibition of Membrane Complement Inhibitor Expression (CD46, CD55, CD59) by siRNA Sensitizes Tumor Cells to Complement Attack In Vitro
pp. 922-931(10)
Authors: Geis, N.; Zell, S.; Rutz, R.; Li, W.; Giese, T.; Mamidi, S.; Schultz, S.; Kirschfink, M.

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Tumor-Targeted Inhibition by a Novel Strategy - Mimoretrovirus Expressing siRNA Targeting the Pokemon Gene
pp. 932-941(10)
Authors: Tian, Z.; Wang, H.; Jia, Z.; Shi, J.; Tang, J.; Mao, L.; Liu, H.; Deng, Y.; He, Y.; Ruan, Z.; Li, J.; Wu, Y.; Ni, B.

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