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Current Cancer Drug Targets aims to cover all the latest and outstanding developments on the medicinal chemistry, pharmacology, molecular biology, genomics and biochemistry of contemporary molecular drug targets involved in cancer, e.g. disease specific proteins, receptors, enzymes, genes.
Each issue of the journal contains a series of timely in-depth reviews written by leaders in the field covering a range of current topics on drug targets involved in cancer.
As the discovery, identification, characterization and validation of novel human drug targets for anti-cancer drug discovery continues to grow; this journal has become essential reading for all pharmaceutical scientists involved in drug discovery and development.

Publisher: Bentham Science Publishers

Volume 10, Number 4, June 2010

Articles

Inhibitors of the Sphingosine Kinase Pathway as Potential Therapeutics
pp. 354-367(14)
Authors: Pitman, M.R.; Pitson, S.M.

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Pharmacological Inhibition of Poly(ADP-ribose) Polymerase (PARP) Activity in PARP-1 Silenced Tumour Cells Increases Chemosensitivity to Temozolomide and to a N3-Adenine Selective Methylating Agent
pp. 368-383(16)
Authors: Tentori, L.; Muzi, A.; Dorio, A.S.; Scarsella, M.; Leonetti, C.; Shah, G.M.; Xu, W.; Camaioni, E.; Gold, B.; Pellicciari, R.; Dantzer, F.; Zhang, J.; Graziani, G.

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Targeting CREB for Cancer Therapy: Friend or Foe
pp. 384-391(8)
Authors: Xiao, X.; Li, B.X.; Mitton, B.; Ikeda, A.; Sakamoto, K.M.

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Molecular Pathways in the Progression of Hormone-Independent and Metastatic Prostate Cancer
pp. 392-401(10)
Authors: Wegiel, B.; Evans, S.; Hellsten, R.; Otterbein, L.E.; Bjartell, A.; Persson, J.L.

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Recent Advances in Understanding Hormonal Therapy Resistant Prostate Cancer
pp. 402-410(9)
Authors: Donkena, K.V.; Yuan, H.; Young, C.Y.

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Human Mesenchymal Stem Cells (hMSCs) as Targets of DNA Damaging Agents in Cancer Therapy
pp. 411-421(11)
Authors: Cruet-Hennequart, S.; Prendergast, A.M.; Barry, F.P.; Carty, M.P.

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Tyrosine Kinase Inhibitors Gefitinib, Lapatinib and Sorafenib Induce Rapid Functional Alterations in Breast Cancer Cells
pp. 422-431(10)
Authors: Carloni, S.; Fabbri, F.; Brigliadori, G.; Ulivi, P.; Silvestrini, R.; Amadori, D.; Zoli, W.

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