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Current Cancer Drug Targets aims to cover all the latest and outstanding developments on the medicinal chemistry, pharmacology, molecular biology, genomics and biochemistry of contemporary molecular drug targets involved in cancer, e.g. disease specific proteins, receptors, enzymes, genes.
Each issue of the journal contains a series of timely in-depth reviews written by leaders in the field covering a range of current topics on drug targets involved in cancer.
As the discovery, identification, characterization and validation of novel human drug targets for anti-cancer drug discovery continues to grow; this journal has become essential reading for all pharmaceutical scientists involved in drug discovery and development.

Publisher: Bentham Science Publishers

Volume 8, Number 8, December 2008

Articles

mTOR Pathway and mTOR Inhibitors as Agents for Cancer Therapy
pp. 647-665(19)
Authors: Baldo, Paolo; Cecco, Sara; Giacomin, Elisa; Lazzarini, Renzo; Ros, Barbara; Marastoni, Stefano

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Anticancer Immunotherapy in Combination with Proapoptotic Therapy
pp. 666-675(10)
Authors: Bruserud, Oystein; Ersvaer, Elisabeth; Olsnes, Astrid; Gjertsen, Bjorn T.

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Anti-Angiogenic Targets in the Treatment of Advanced Renal Cell Carcinoma
pp. 676-682(7)
Authors: Heng, Daniel Y.C.; Bukowski, Ronald M.

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PEDF as an Emerging Therapeutic Candidate for Osteosarcoma
pp. 683-690(8)
Authors: Dass, Crispin R.; Ek, Eugene T.H.; Choong, Peter F.M.

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Melatonin as a Selective Estrogen Enzyme Modulator
pp. 691-702(12)
Authors: Cos, S.; Gonzalez, A.; Martinez-Campa, C.; Mediavilla, M. D.; Alonso-Gonzalez, C.; Sanchez-Barcelo, E. J.

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Budesonide and Phenethyl Isothiocyanate Attenuate DNA Damage in Bronchoalveolar Lavage Cells of Mice Exposed to Environmental Cigarette Smoke
pp. 703-708(6)
Authors: Micale, Rosanna T.; D'Agostini, Francesco; Steele, Vernon E.; Maestra, Sebastiano L.; De Flora, Silvio

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Choline Kinase Alpha Depletion Selectively Kills Tumoral Cells
pp. 709-719(11)
Authors: Banez-Coronel, Monica; de Molina, Ana R.; Rodriguez-Gonzalez, Agustin; Sarmentero, Jacinto; Ramos, MÂȘ Angeles; Garcia-Cabezas, Miguel Angel; Garcia-Oroz, Lourdes; Lacal, Juan Carlos

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ADAM Proteins- Therapeutic Potential in Cancer
pp. 720-732(13)
Authors: Lu, Xinjie; Lu, Dong; Scully, Mike; Kakkar, Vijay

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The PIK3CA Gene as a Mutated Target for Cancer Therapy
pp. 733-740(8)
Authors: Gustin, John P.; Cosgrove, David P.; Park, Ben H.

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Cell Cycle Regulatory Protein 5 (Cdk5) is a Novel Downstream Target of ERK in Carboplatin Induced Death of Breast Cancer Cells (Supplementary Data)
pp. 741-752(12)
Authors: Upadhyay, Ankur K.; Ajay, Amrendra Kumar; Singh, Sandeep; Bhat, Manoj Kumar

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Protective Effect of NSAIDs on Cancer and Influence of COX-2 C
pp. 753-764(12)
Authors: Siemes, C.; Visser, L. E.; Coebergh, J. W.W.; Hofman, A.; Uitterlinden, A. G.; Stricker, B.H. Ch.

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ERRATUM
pp. 765-765(1)

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