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Current Cancer Drug Targets aims to cover all the latest and outstanding developments on the medicinal chemistry, pharmacology, molecular biology, genomics and biochemistry of contemporary molecular drug targets involved in cancer, e.g. disease specific proteins, receptors, enzymes, genes.
Each issue of the journal contains a series of timely in-depth reviews written by leaders in the field covering a range of current topics on drug targets involved in cancer.
As the discovery, identification, characterization and validation of novel human drug targets for anti-cancer drug discovery continues to grow; this journal has become essential reading for all pharmaceutical scientists involved in drug discovery and development.

Publisher: Bentham Science Publishers

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Volume 8, Number 1, February 2008

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Articles

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Advances of AKT Pathway in Human Oncogenesis and as a Target for Anti-Cancer Drug Discovery
pp. 2-6(5)
Authors: Wang, Lu-Hai; Cheng, George Z.; Park, Sungman; Shu, Shaokun; He, Lili; Kong, William; Zhang, Weizhou; Yuan, Zengqiang; Cheng, Jin Q.

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The PI3K/Akt Pathway: Recent Progress in the Development of ATP-Competitive and Allosteric Akt Kinase Inhibitors
pp. 7-18(12)
Authors: Lindsley, Craig W.; Barnett, Stanley F.; Layton, Mark E.; Bilodeau, Mark T.

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AKT Signaling in Regulating Angiogenesis
pp. 19-26(8)
Authors: Jiang, Bing-Hua; Liu, Ling-Zhi

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Deregulation of the Akt Pathway in Human Cancer
pp. 27-36(10)
Authors: Tokunaga, Eriko; Oki, Eiji; Egashira, Akinori; Sadanaga, Noriaki; Morita, Masaru; Kakeji, Yoshihiro; Maehara, Yoshihiko

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Cellular FLICE-Like Inhibitory Protein (C-FLIP): A Novel Target for Cancer Therapy
pp. 37-46(10)
Authors: Safa, Ahmad R.; Day, Travis W.; Wu, Ching-Huang

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Inhibitors of Cyclin Dependent Kinases: Useful Targets for Cancer Treatment
pp. 53-75(23)
Authors: Sharma, P. S.; Sharma, R.; Tyagi, R.

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Small Molecule Tyrosine Kinase Inhibitors: Potential Role in Pediatric Malignant Solid Tumors
pp. 76-85(10)
Authors: Rossler, Jochen; Geoerger, Birgit; Taylor, Melissa; Vassal, Gilles

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